Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1834

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ofloxacin 0.8 ug/mL
2,078,865	+				-1.3
2,078,866	-				+1.6
2,079,191	-		Rv1833c	0.30	-0.1
2,079,250	-		Rv1833c	0.37	-0.4
2,079,641	+		Rv1833c	0.83	-1.5
2,079,642	-		Rv1833c	0.83	-0.1
2,079,790	+				+0.5
2,080,281	+		Rv1834	0.52	+0.2
2,080,282	-		Rv1834	0.52	-0.8
2,080,282	-		Rv1834	0.52	-0.4
2,080,457	+		Rv1834	0.72	+0.3
2,080,458	-		Rv1834	0.72	+0.1
2,080,458	-		Rv1834	0.72	-3.3
2,080,661	+				-0.2
2,080,662	-				+3.4
2,080,710	+				-0.8
2,080,710	+				+0.0
2,080,711	-				-1.1
2,080,711	-				+0.4
2,080,753	+				+0.1
2,080,852	+				-0.1
2,080,853	-				-1.7
2,080,853	-				+2.4
2,080,902	+		Rv1835c	0.11	+0.5
2,080,995	+		Rv1835c	0.16	+2.1
2,080,995	+		Rv1835c	0.16	-0.3
2,080,996	-		Rv1835c	0.16	+0.2
2,080,996	-		Rv1835c	0.16	+0.4
2,080,996	-		Rv1835c	0.16	-0.1
2,081,014	+		Rv1835c	0.17	-0.1
2,081,015	-		Rv1835c	0.17	-0.1
2,081,015	-		Rv1835c	0.17	+0.2
2,081,051	-		Rv1835c	0.19	+0.4
2,081,088	-		Rv1835c	0.21	-0.8
2,081,088	-		Rv1835c	0.21	-0.8
2,081,147	+		Rv1835c	0.24	+0.1
2,081,148	-		Rv1835c	0.24	+0.1
2,081,149	+		Rv1835c	0.24	-0.7
2,081,150	-		Rv1835c	0.24	-0.0
2,081,150	-		Rv1835c	0.24	+0.1
2,081,150	-		Rv1835c	0.24	+0.1
2,081,266	+		Rv1835c	0.30	+0.1
2,081,266	+		Rv1835c	0.30	+0.9
2,081,266	+		Rv1835c	0.30	-1.1
2,081,267	-		Rv1835c	0.30	+0.1
2,081,330	-		Rv1835c	0.33	-0.2
2,081,332	+		Rv1835c	0.33	+0.5
2,081,332	+		Rv1835c	0.33	-0.4
2,081,332	+		Rv1835c	0.33	-0.6
2,081,333	-		Rv1835c	0.33	+0.3
2,081,333	-		Rv1835c	0.33	-0.6
2,081,333	-		Rv1835c	0.33	-0.2
2,081,333	-		Rv1835c	0.33	+0.3
2,081,402	-		Rv1835c	0.37	-0.9
2,081,614	+		Rv1835c	0.48	-0.1
2,081,615	-		Rv1835c	0.48	-1.3
2,081,639	-		Rv1835c	0.50	+0.9
2,081,639	-		Rv1835c	0.50	+1.6
2,081,639	-		Rv1835c	0.50	+1.6
2,081,680	+		Rv1835c	0.52	-0.1