Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0632c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0631c and Rv0632c are separated by 276 nucleotidesRv0632c and Rv0633c are separated by 48 nucleotides Rv0631c: Rv0631c - Probable exonuclease V (gamma chain) RecC (exodeoxyribonuclease V gamma chain)(exodeoxyribonuclease V polypeptide), at 725,013 to 728,306 Rv0631c Rv0632c: Rv0632c - Probable enoyl-CoA hydratase EchA3 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 728,583 to 729,278 Rv0632c Rv0633c: Rv0633c - Possible exported protein, at 729,327 to 730,166 Rv0633c Position (kb) 728 729 730Strain fitness (log2 ratio) -2 -1 0 1at 727.861 kb on + strand, within Rv0631cat 727.862 kb on - strand, within Rv0631cat 728.360 kb on - strandat 728.360 kb on - strandat 728.360 kb on - strandat 728.540 kb on + strandat 728.585 kb on - strandat 728.908 kb on + strand, within Rv0632cat 728.909 kb on - strand, within Rv0632cat 729.020 kb on - strand, within Rv0632cat 729.257 kb on + strandat 729.260 kb on - strandat 729.260 kb on - strandat 729.328 kb on + strandat 729.508 kb on + strand, within Rv0633cat 729.508 kb on + strand, within Rv0633cat 729.521 kb on + strand, within Rv0633cat 729.522 kb on - strand, within Rv0633cat 729.522 kb on - strand, within Rv0633cat 729.522 kb on - strand, within Rv0633cat 729.525 kb on + strand, within Rv0633cat 729.526 kb on - strand, within Rv0633cat 729.691 kb on + strand, within Rv0633cat 729.692 kb on - strand, within Rv0633cat 729.694 kb on + strand, within Rv0633cat 729.695 kb on - strand, within Rv0633cat 729.838 kb on + strand, within Rv0633cat 729.905 kb on - strand, within Rv0633cat 729.934 kb on - strand, within Rv0633cat 729.989 kb on - strand, within Rv0633cat 729.989 kb on - strand, within Rv0633cat 730.172 kb on + strandat 730.173 kb on - strandat 730.173 kb on - strandat 730.173 kb on - strandat 730.174 kb on + strandat 730.201 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
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727,861 + Rv0631c 0.86 -0.3
727,862 - Rv0631c 0.86 +0.2
728,360 - -0.4
728,360 - -2.1
728,360 - -1.2
728,540 + -0.5
728,585 - -1.3
728,908 + Rv0632c 0.47 +0.9
728,909 - Rv0632c 0.47 +0.5
729,020 - Rv0632c 0.63 -0.3
729,257 + -1.2
729,260 - -0.8
729,260 - -0.6
729,328 + -1.3
729,508 + Rv0633c 0.22 +0.2
729,508 + Rv0633c 0.22 -2.2
729,521 + Rv0633c 0.23 -0.2
729,522 - Rv0633c 0.23 -1.2
729,522 - Rv0633c 0.23 -0.4
729,522 - Rv0633c 0.23 -0.3
729,525 + Rv0633c 0.24 -0.5
729,526 - Rv0633c 0.24 -0.4
729,691 + Rv0633c 0.43 -0.8
729,692 - Rv0633c 0.43 +0.8
729,694 + Rv0633c 0.44 -0.2
729,695 - Rv0633c 0.44 -0.0
729,838 + Rv0633c 0.61 +1.0
729,905 - Rv0633c 0.69 -1.4
729,934 - Rv0633c 0.72 -0.3
729,989 - Rv0633c 0.79 -0.5
729,989 - Rv0633c 0.79 -0.5
730,172 + -0.7
730,173 - -1.5
730,173 - -0.7
730,173 - +0.5
730,174 + -1.5
730,201 + -0.9

Or see this region's nucleotide sequence