Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0428c

Experiment: 7H9 with Ofloxacin 0.8 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0427c and Rv0428c are separated by 2 nucleotidesRv0428c and Rv0429c overlap by 1 nucleotidesRv0429c and Rv0430 are separated by 336 nucleotides Rv0427c: Rv0427c - Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI), at 516,017 to 516,892 Rv0427c Rv0428c: Rv0428c - GCN5-related N-acetyltransferase, at 516,895 to 517,803 Rv0428c Rv0429c: Rv0429c - Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase), at 517,803 to 518,396 Rv0429c Rv0430: Rv0430 - Conserved hypothetical protein, at 518,733 to 519,041 Rv0430 Position (kb) 516 517 518Strain fitness (log2 ratio) -2 -1 0 1at 516.199 kb on - strand, within Rv0427cat 516.230 kb on + strand, within Rv0427cat 516.441 kb on + strand, within Rv0427cat 516.669 kb on + strand, within Rv0427cat 516.896 kb on + strandat 516.904 kb on - strandat 516.932 kb on + strandat 517.007 kb on + strand, within Rv0428cat 517.181 kb on + strand, within Rv0428cat 517.181 kb on + strand, within Rv0428cat 517.182 kb on - strand, within Rv0428cat 517.182 kb on - strand, within Rv0428cat 517.235 kb on - strand, within Rv0428cat 517.465 kb on - strand, within Rv0428cat 517.474 kb on + strand, within Rv0428cat 517.495 kb on + strand, within Rv0428cat 517.760 kb on + strandat 518.405 kb on - strandat 518.409 kb on + strandat 518.410 kb on - strandat 518.424 kb on + strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL
remove
516,199 - Rv0427c 0.21 -0.1
516,230 + Rv0427c 0.24 +0.1
516,441 + Rv0427c 0.48 +0.8
516,669 + Rv0427c 0.74 -0.4
516,896 + +0.4
516,904 - +1.0
516,932 + -2.0
517,007 + Rv0428c 0.12 -0.8
517,181 + Rv0428c 0.31 +0.1
517,181 + Rv0428c 0.31 -0.1
517,182 - Rv0428c 0.32 -1.1
517,182 - Rv0428c 0.32 -2.7
517,235 - Rv0428c 0.37 -1.8
517,465 - Rv0428c 0.63 -0.3
517,474 + Rv0428c 0.64 -0.8
517,495 + Rv0428c 0.66 -2.2
517,760 + -0.6
518,405 - +1.3
518,409 + -0.2
518,410 - -0.1
518,424 + -0.3

Or see this region's nucleotide sequence