Experiment: 7H9 with Ofloxacin 0.8 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0320 and Rv0321 are separated by 31 nucleotides Rv0321 and Rv0322 are separated by 105 nucleotides Rv0322 and Rv0323c overlap by 12 nucleotides Rv0323c and Rv0324 are separated by 100 nucleotides
Rv0320: Rv0320 - Possible conserved exported protein, at 387,888 to 388,550
Rv0320
Rv0321: Rv0321 - Probable deoxycytidine triphosphate deaminase Dcd (dCTP deaminase), at 388,582 to 389,154
Rv0321
Rv0322: Rv0322 - Probable UDP-glucose 6-dehydrogenase UdgA (UDP-GLC dehydrogenase) (UDP-GLCDH) (UDPGDH), at 389,260 to 390,591
Rv0322
Rv0323c: Rv0323c - Conserved hypothetical protein, at 390,580 to 391,251
Rv0323c
Rv0324: Rv0324 - Possible transcriptional regulatory protein (possibly ArsR-family), at 391,352 to 392,032
Rv0324
Position (kb) 389
390
391 Strain fitness (log2 ratio) -3
-2
-1
0
1 at 388.388 kb on - strand, within Rv0320 at 388.388 kb on - strand, within Rv0320 at 388.441 kb on - strand, within Rv0320 at 388.441 kb on - strand, within Rv0320 at 388.441 kb on - strand, within Rv0320 at 388.443 kb on + strand, within Rv0320 at 388.443 kb on + strand, within Rv0320 at 388.443 kb on + strand, within Rv0320 at 388.443 kb on + strand, within Rv0320 at 388.443 kb on + strand, within Rv0320 at 388.444 kb on - strand, within Rv0320 at 388.444 kb on - strand, within Rv0320 at 388.444 kb on - strand, within Rv0320 at 388.539 kb on + strand at 388.539 kb on + strand at 388.540 kb on - strand at 388.570 kb on + strand at 388.570 kb on + strand at 388.570 kb on + strand at 388.571 kb on - strand at 388.571 kb on - strand at 388.571 kb on - strand at 388.571 kb on - strand at 388.724 kb on - strand, within Rv0321 at 388.887 kb on + strand, within Rv0321 at 388.970 kb on + strand, within Rv0321 at 389.093 kb on - strand, within Rv0321 at 389.093 kb on - strand, within Rv0321 at 389.148 kb on + strand at 389.148 kb on + strand at 389.149 kb on - strand at 389.152 kb on + strand at 389.153 kb on - strand at 389.153 kb on - strand at 389.247 kb on + strand at 389.247 kb on + strand at 389.313 kb on + strand at 389.362 kb on - strand at 389.398 kb on + strand, within Rv0322 at 389.431 kb on - strand, within Rv0322 at 389.537 kb on - strand, within Rv0322 at 389.805 kb on - strand, within Rv0322 at 390.370 kb on - strand, within Rv0322 at 390.380 kb on - strand, within Rv0322 at 390.473 kb on + strand at 390.473 kb on + strand at 390.611 kb on + strand at 390.612 kb on - strand at 390.612 kb on - strand at 390.612 kb on - strand at 390.914 kb on - strand, within Rv0323c at 390.980 kb on - strand, within Rv0323c at 391.303 kb on + strand at 391.584 kb on - strand, within Rv0324
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL remove 388,388 - Rv0320 0.75 +0.7 388,388 - Rv0320 0.75 -0.2 388,441 - Rv0320 0.83 -0.4 388,441 - Rv0320 0.83 +1.6 388,441 - Rv0320 0.83 +0.8 388,443 + Rv0320 0.84 +0.2 388,443 + Rv0320 0.84 -0.3 388,443 + Rv0320 0.84 +0.0 388,443 + Rv0320 0.84 -0.1 388,443 + Rv0320 0.84 +0.6 388,444 - Rv0320 0.84 -1.4 388,444 - Rv0320 0.84 -1.6 388,444 - Rv0320 0.84 +0.2 388,539 + +0.1 388,539 + +0.5 388,540 - +0.6 388,570 + -0.3 388,570 + -0.4 388,570 + -0.4 388,571 - -0.3 388,571 - +0.3 388,571 - +1.2 388,571 - +0.4 388,724 - Rv0321 0.25 -3.0 388,887 + Rv0321 0.53 -1.0 388,970 + Rv0321 0.68 +0.5 389,093 - Rv0321 0.89 +0.3 389,093 - Rv0321 0.89 +0.3 389,148 + -0.4 389,148 + -0.9 389,149 - +0.1 389,152 + -0.2 389,153 - -0.6 389,153 - +0.3 389,247 + -0.3 389,247 + -0.4 389,313 + -2.0 389,362 - -2.1 389,398 + Rv0322 0.10 -0.1 389,431 - Rv0322 0.13 -0.6 389,537 - Rv0322 0.21 -1.0 389,805 - Rv0322 0.41 -1.0 390,370 - Rv0322 0.83 -2.2 390,380 - Rv0322 0.84 +0.2 390,473 + -1.1 390,473 + -0.7 390,611 + +0.3 390,612 - +0.3 390,612 - +0.0 390,612 - +1.4 390,914 - Rv0323c 0.50 -0.4 390,980 - Rv0323c 0.60 -1.3 391,303 + -0.9 391,584 - Rv0324 0.34 +0.0
Or see this region's nucleotide sequence