Experiment: 7H9 with Ofloxacin 0.8 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0278c and Rv0279c are separated by 249 nucleotides Rv0279c and Rv0280 are separated by 290 nucleotides
Rv0278c: Rv0278c - PE-PGRS family protein PE_PGRS3, at 333,437 to 336,310
Rv0278c
Rv0279c: Rv0279c - PE-PGRS family protein PE_PGRS4, at 336,560 to 339,073
Rv0279c
Rv0280: Rv0280 - PPE family protein PPE3, at 339,364 to 340,974
Rv0280
Position (kb) 336
337
338
339
340 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3 at 335.679 kb on - strand, within Rv0278c at 335.681 kb on + strand, within Rv0278c at 335.682 kb on - strand, within Rv0278c at 336.051 kb on + strand at 336.382 kb on + strand at 336.383 kb on - strand at 336.452 kb on - strand at 336.561 kb on + strand at 336.561 kb on + strand at 336.562 kb on - strand at 336.896 kb on + strand, within Rv0279c at 336.896 kb on + strand, within Rv0279c at 336.896 kb on + strand, within Rv0279c at 336.896 kb on + strand, within Rv0279c at 336.897 kb on - strand, within Rv0279c at 336.897 kb on - strand, within Rv0279c at 336.897 kb on - strand, within Rv0279c at 336.947 kb on + strand, within Rv0279c at 336.947 kb on + strand, within Rv0279c at 336.948 kb on - strand, within Rv0279c at 337.223 kb on - strand, within Rv0279c at 337.438 kb on + strand, within Rv0279c at 337.439 kb on - strand, within Rv0279c at 337.703 kb on + strand, within Rv0279c at 337.704 kb on - strand, within Rv0279c at 337.704 kb on - strand, within Rv0279c at 337.704 kb on - strand, within Rv0279c at 337.763 kb on - strand, within Rv0279c at 338.192 kb on + strand, within Rv0279c at 338.193 kb on - strand, within Rv0279c at 338.209 kb on + strand, within Rv0279c at 338.889 kb on + strand at 339.154 kb on + strand at 339.182 kb on - strand at 339.504 kb on - strand at 339.559 kb on + strand, within Rv0280 at 339.559 kb on + strand, within Rv0280 at 339.560 kb on - strand, within Rv0280 at 339.560 kb on - strand, within Rv0280 at 339.560 kb on - strand, within Rv0280 at 339.594 kb on - strand, within Rv0280 at 339.784 kb on + strand, within Rv0280 at 339.826 kb on + strand, within Rv0280 at 339.826 kb on + strand, within Rv0280 at 339.827 kb on - strand, within Rv0280 at 339.962 kb on - strand, within Rv0280 at 339.962 kb on - strand, within Rv0280 at 339.977 kb on + strand, within Rv0280 at 340.054 kb on + strand, within Rv0280 at 340.056 kb on + strand, within Rv0280
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ofloxacin 0.8 ug/mL remove 335,679 - Rv0278c 0.78 +0.5 335,681 + Rv0278c 0.78 +1.3 335,682 - Rv0278c 0.78 -1.0 336,051 + -2.4 336,382 + +3.0 336,383 - -0.1 336,452 - +0.6 336,561 + +0.8 336,561 + +2.3 336,562 - +1.0 336,896 + Rv0279c 0.13 +0.7 336,896 + Rv0279c 0.13 +0.9 336,896 + Rv0279c 0.13 +0.6 336,896 + Rv0279c 0.13 -0.4 336,897 - Rv0279c 0.13 +0.0 336,897 - Rv0279c 0.13 +1.2 336,897 - Rv0279c 0.13 -0.7 336,947 + Rv0279c 0.15 +2.4 336,947 + Rv0279c 0.15 +0.3 336,948 - Rv0279c 0.15 +2.2 337,223 - Rv0279c 0.26 -3.0 337,438 + Rv0279c 0.35 +1.0 337,439 - Rv0279c 0.35 +0.9 337,703 + Rv0279c 0.45 +1.0 337,704 - Rv0279c 0.46 +1.5 337,704 - Rv0279c 0.46 +0.6 337,704 - Rv0279c 0.46 -0.2 337,763 - Rv0279c 0.48 -3.5 338,192 + Rv0279c 0.65 +0.8 338,193 - Rv0279c 0.65 +1.1 338,209 + Rv0279c 0.66 -0.3 338,889 + +1.9 339,154 + -0.3 339,182 - +1.1 339,504 - +0.6 339,559 + Rv0280 0.12 +1.6 339,559 + Rv0280 0.12 +0.9 339,560 - Rv0280 0.12 +0.2 339,560 - Rv0280 0.12 +0.7 339,560 - Rv0280 0.12 +1.0 339,594 - Rv0280 0.14 +2.3 339,784 + Rv0280 0.26 +0.6 339,826 + Rv0280 0.29 +0.4 339,826 + Rv0280 0.29 +0.5 339,827 - Rv0280 0.29 -1.5 339,962 - Rv0280 0.37 +0.8 339,962 - Rv0280 0.37 +0.9 339,977 + Rv0280 0.38 +0.9 340,054 + Rv0280 0.43 +1.5 340,056 + Rv0280 0.43 +0.6
Or see this region's nucleotide sequence