Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3921c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3919c and Rv3920c are separated by 131 nucleotidesRv3920c and Rv3921c are separated by 71 nucleotidesRv3921c and Rv3922c overlap by 17 nucleotidesRv3922c and Rv3923c overlap by 4 nucleotidesRv3923c and Rv3924c overlap by 4 nucleotides Rv3919c: Rv3919c - Probable glucose-inhibited division protein B Gid, at 4,407,528 to 4,408,202 Rv3919c Rv3920c: Rv3920c - Conserved protein similar to jag protein, at 4,408,334 to 4,408,897 Rv3920c Rv3921c: Rv3921c - Probable conserved transmembrane protein, at 4,408,969 to 4,410,069 Rv3921c Rv3922c: Rv3922c - Possible hemolysin, at 4,410,053 to 4,410,415 Rv3922c Rv3923c: Rv3923c - Ribonuclease P protein component RnpA (RNaseP protein) (RNase P protein) (protein C5), at 4,410,412 to 4,410,789 Rv3923c Rv3924c: Rv3924c - 50S ribosomal protein L34 RpmH, at 4,410,786 to 4,410,929 Rv3924c Position (kb) 4408 4409 4410 4411Strain fitness (log2 ratio) -2 -1 0 1at 4408.056 kb on + strand, within Rv3919cat 4408.071 kb on + strand, within Rv3919cat 4408.072 kb on - strand, within Rv3919cat 4408.077 kb on - strand, within Rv3919cat 4408.203 kb on + strandat 4408.203 kb on + strandat 4408.203 kb on + strandat 4408.204 kb on - strandat 4408.299 kb on + strandat 4408.300 kb on - strandat 4408.336 kb on - strandat 4408.553 kb on + strand, within Rv3920cat 4408.554 kb on - strand, within Rv3920cat 4408.554 kb on - strand, within Rv3920cat 4410.241 kb on - strand, within Rv3922cat 4410.265 kb on - strand, within Rv3922cat 4410.272 kb on - strand, within Rv3922cat 4410.272 kb on - strand, within Rv3922cat 4410.272 kb on - strand, within Rv3922cat 4410.278 kb on - strand, within Rv3922cat 4410.368 kb on - strand, within Rv3922cat 4410.770 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL
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4,408,056 + Rv3919c 0.78 -1.1
4,408,071 + Rv3919c 0.80 -0.3
4,408,072 - Rv3919c 0.81 +0.5
4,408,077 - Rv3919c 0.81 +0.5
4,408,203 + +0.9
4,408,203 + +0.7
4,408,203 + +0.4
4,408,204 - -1.8
4,408,299 + -1.4
4,408,300 - -1.0
4,408,336 - -1.1
4,408,553 + Rv3920c 0.39 -1.0
4,408,554 - Rv3920c 0.39 -1.6
4,408,554 - Rv3920c 0.39 +0.0
4,410,241 - Rv3922c 0.52 -1.2
4,410,265 - Rv3922c 0.58 -0.2
4,410,272 - Rv3922c 0.60 +0.8
4,410,272 - Rv3922c 0.60 -1.2
4,410,272 - Rv3922c 0.60 +0.6
4,410,278 - Rv3922c 0.62 +0.4
4,410,368 - Rv3922c 0.87 +0.8
4,410,770 - -1.2

Or see this region's nucleotide sequence