Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3479

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
3,894,846	+		Rv3478	0.36	+1.5
3,894,847	-		Rv3478	0.36	+0.8
3,894,847	-		Rv3478	0.36	+0.2
3,894,883	-		Rv3478	0.39	-0.3
3,895,082	-		Rv3478	0.55	+0.9
3,895,232	-		Rv3478	0.68	-0.7
3,895,940	+				+0.9
3,895,951	-				+0.1
3,895,951	-				-0.2
3,895,951	-				+1.0
3,896,147	+		Rv3479	0.11	+0.7
3,896,163	+		Rv3479	0.11	+0.4
3,896,261	+		Rv3479	0.14	+0.1
3,896,262	-		Rv3479	0.14	-0.7
3,896,406	+		Rv3479	0.19	-0.8
3,896,652	+		Rv3479	0.27	+0.4
3,896,652	+		Rv3479	0.27	+1.3
3,896,653	-		Rv3479	0.27	-0.5
3,897,318	+		Rv3479	0.49	+0.3
3,897,319	-		Rv3479	0.49	-0.4
3,897,335	-		Rv3479	0.49	+0.0
3,897,396	-		Rv3479	0.51	-0.9
3,897,567	-		Rv3479	0.57	-0.9
3,897,575	+		Rv3479	0.57	-0.5
3,897,587	+		Rv3479	0.58	-0.1
3,897,809	+		Rv3479	0.65	+0.5
3,897,810	-		Rv3479	0.65	-0.4
3,898,269	+		Rv3479	0.80	+0.2
3,898,438	-		Rv3479	0.85	-0.1
3,898,545	+		Rv3479	0.89	-0.3
3,898,731	+				+1.7
3,899,042	+				+1.6
3,899,252	+		Rv3480c	0.23	-2.1
3,899,617	+		Rv3480c	0.47	-1.0
3,899,618	-		Rv3480c	0.47	-1.8
3,899,741	-		Rv3480c	0.56	-0.1
3,899,824	+		Rv3480c	0.61	-1.1
3,899,824	+		Rv3480c	0.61	-1.1