Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3180c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
3,548,309	-		Rv3179	0.54	+1.8
3,548,416	+		Rv3179	0.62	+0.1
3,548,417	-		Rv3179	0.62	+0.5
3,548,417	-		Rv3179	0.62	+0.3
3,548,423	+		Rv3179	0.62	+0.8
3,548,424	-		Rv3179	0.62	-0.5
3,548,424	-		Rv3179	0.62	-0.7
3,548,424	-		Rv3179	0.62	+3.3
3,548,609	+		Rv3179	0.77	+2.0
3,548,609	+		Rv3179	0.77	+1.8
3,548,641	+		Rv3179	0.79	-0.8
3,548,642	-		Rv3179	0.79	+3.6
3,548,815	+				-0.8
3,548,815	+				-0.7
3,548,905	+				-0.5
3,548,906	-				-0.2
3,548,906	-				-1.0
3,548,906	-				-0.6
3,548,913	+				+0.8
3,548,925	+				+0.2
3,549,005	-				-0.8
3,549,042	+				+0.0
3,549,109	+				-0.1
3,549,110	-				-0.9
3,549,110	-				-1.5
3,549,336	-		Rv3180c	0.19	-0.2
3,549,395	+		Rv3180c	0.32	+0.7
3,549,518	+		Rv3180c	0.61	-0.5
3,549,519	-		Rv3180c	0.61	+1.8
3,549,608	+		Rv3180c	0.81	+1.7
3,549,609	-		Rv3180c	0.82	+1.9
3,549,675	+				-1.4
3,549,944	-		Rv3181c	0.56	+0.3
3,550,257	-				-0.4
3,550,345	-				-1.3
3,550,468	-		Rv3182	0.27	+0.3