Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2776c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
3,082,454	-		Rv2774c	0.25	+2.3
3,082,454	-		Rv2774c	0.25	+0.8
3,082,800	+				+0.1
3,082,801	-				-0.8
3,082,804	+				-0.4
3,082,805	-				+0.5
3,082,805	-				+0.0
3,082,861	-				+0.2
3,082,961	+		Rv2775	0.11	+1.3
3,083,037	+		Rv2775	0.28	-0.7
3,083,038	-		Rv2775	0.28	+0.3
3,083,131	+		Rv2775	0.48	+0.1
3,083,131	+		Rv2775	0.48	-0.1
3,083,132	-		Rv2775	0.48	-0.2
3,083,132	-		Rv2775	0.48	-2.3
3,083,257	+		Rv2775	0.75	+0.0
3,083,347	+				-0.4
3,083,660	+		Rv2776c	0.31	-0.2
3,083,710	+		Rv2776c	0.36	-0.6
3,083,711	-		Rv2776c	0.36	+2.3
3,083,735	+		Rv2776c	0.39	+0.0
3,083,736	-		Rv2776c	0.39	-0.5
3,083,842	+		Rv2776c	0.50	-2.6
3,084,117	+		Rv2776c	0.80	-0.7
3,084,146	+		Rv2776c	0.83	-0.5
3,084,146	+		Rv2776c	0.83	-0.8
3,084,276	+				-0.8
3,084,364	+				+0.1
3,084,365	-				+0.1
3,084,365	-				-2.1
3,084,365	-				-0.7
3,084,427	-				-1.2
3,084,469	+				+0.1
3,084,470	-				-0.5
3,084,522	+				+0.5
3,084,523	-				-0.5
3,084,576	+				+0.0
3,084,576	+				-1.4
3,084,576	+				-0.3
3,084,580	-				-0.7
3,084,682	-		Rv2777c	0.18	-1.8
3,084,696	+		Rv2777c	0.20	+0.3
3,084,697	-		Rv2777c	0.20	+2.3
3,084,930	+		Rv2777c	0.42	+0.2
3,084,930	+		Rv2777c	0.42	-0.4
3,084,965	+		Rv2777c	0.45	-1.0
3,084,966	-		Rv2777c	0.45	+3.3
3,084,978	+		Rv2777c	0.46	+0.7
3,084,979	-		Rv2777c	0.46	-0.5
3,084,979	-		Rv2777c	0.46	-1.0
3,084,979	-		Rv2777c	0.46	+0.3
3,085,048	+		Rv2777c	0.53	-0.7
3,085,232	-		Rv2777c	0.70	+0.0
3,085,232	-		Rv2777c	0.70	-0.2
3,085,278	+		Rv2777c	0.74	+0.3
3,085,278	+		Rv2777c	0.74	-0.2
3,085,278	+		Rv2777c	0.74	-0.4
3,085,278	+		Rv2777c	0.74	-0.0
3,085,279	-		Rv2777c	0.74	+1.3
3,085,279	-		Rv2777c	0.74	-0.7
3,085,279	-		Rv2777c	0.74	+0.8