Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2639c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
2,964,070	-		Rv2637	0.74	-0.5
2,964,149	+		Rv2637	0.86	+0.2
2,964,382	-				-0.9
2,964,434	+				-0.1
2,964,435	-				-0.7
2,964,472	+		Rv2638	0.15	-0.8
2,964,472	+		Rv2638	0.15	-0.6
2,964,473	-		Rv2638	0.15	-0.3
2,964,473	-		Rv2638	0.15	+2.3
2,964,796	-		Rv2638	0.87	-2.8
2,964,796	-		Rv2638	0.87	-0.7
2,964,809	+				-0.9
2,964,897	+				-0.5
2,964,969	-				+0.6
2,965,046	-				+1.3
2,965,166	-		Rv2639c	0.42	+2.6
2,965,166	-		Rv2639c	0.42	-0.3
2,965,222	+		Rv2639c	0.59	-0.8
2,965,222	+		Rv2639c	0.59	-0.7
2,965,223	-		Rv2639c	0.59	+0.9
2,965,223	-		Rv2639c	0.59	+0.8
2,965,290	+		Rv2639c	0.79	+1.3
2,965,291	-		Rv2639c	0.80	+0.3
2,965,370	+				-0.0
2,965,459	+				-0.0
2,965,459	+				+0.1
2,965,465	+				-1.8
2,965,465	+				-0.5
2,965,465	+				+0.7
2,965,466	-				-0.0
2,965,466	-				+0.4
2,965,466	-				-1.1
2,965,466	-				+2.3
2,965,466	-				+0.2
2,965,868	-				-0.5
2,965,881	-				-0.7
2,965,934	+				-0.4
2,965,934	+				+1.3
2,965,956	-				-1.1
2,965,956	-				+1.3
2,965,996	+		Rv2641	0.12	-0.8
2,965,997	-		Rv2641	0.13	-0.0
2,966,074	-		Rv2641	0.29	+0.3
2,966,074	-		Rv2641	0.29	+0.1
2,966,074	-		Rv2641	0.29	+1.3
2,966,281	+		Rv2641	0.75	+0.1
2,966,281	+		Rv2641	0.75	+0.2
2,966,282	-		Rv2641	0.75	+0.7
2,966,283	+		Rv2641	0.75	-1.5
2,966,283	+		Rv2641	0.75	-0.2
2,966,283	+		Rv2641	0.75	-0.7
2,966,284	-		Rv2641	0.75	+0.3