Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2394

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
2,687,971	+				+0.4
2,688,248	-		Rv2394	0.12	+0.3
2,688,297	-		Rv2394	0.15	-0.2
2,688,394	+		Rv2394	0.20	+0.7
2,688,403	+		Rv2394	0.20	-0.0
2,688,403	+		Rv2394	0.20	+2.3
2,688,403	+		Rv2394	0.20	-0.8
2,688,404	-		Rv2394	0.20	-1.0
2,688,478	+		Rv2394	0.24	+0.4
2,688,478	+		Rv2394	0.24	+0.1
2,688,479	-		Rv2394	0.24	+1.3
2,688,479	-		Rv2394	0.24	+1.0
2,688,734	-		Rv2394	0.37	-0.6
2,688,734	-		Rv2394	0.37	-0.0
2,689,168	+		Rv2394	0.60	-0.3
2,689,168	+		Rv2394	0.60	+0.1
2,689,168	+		Rv2394	0.60	+0.6
2,689,169	-		Rv2394	0.60	+0.0
2,689,170	+		Rv2394	0.60	+0.4
2,689,170	+		Rv2394	0.60	+1.3
2,689,170	+		Rv2394	0.60	-0.0
2,689,171	-		Rv2394	0.60	-0.6
2,689,234	+		Rv2394	0.63	-0.1
2,689,234	+		Rv2394	0.63	-1.1
2,689,234	+		Rv2394	0.63	+0.0
2,689,256	+		Rv2394	0.64	-0.7
2,689,372	+		Rv2394	0.70	-1.7
2,689,372	+		Rv2394	0.70	-0.5
2,689,423	+		Rv2394	0.73	+0.6
2,689,489	-		Rv2394	0.77	-0.3
2,689,598	-		Rv2394	0.82	+0.0
2,689,738	-		Rv2394	0.89	+0.4
2,689,831	-				-0.1
2,690,051	+				+1.0
2,690,065	+				+0.5
2,690,137	+				+1.7
2,690,137	+				-1.4
2,690,137	+				-0.3
2,690,137	+				-0.7
2,690,166	-				-0.4
2,690,166	-				+2.3
2,690,175	+				+1.1
2,690,272	+				-0.4
2,690,272	+				+0.3
2,690,273	-		Rv2395	0.10	-1.0
2,690,420	+		Rv2395	0.17	+0.2
2,690,421	-		Rv2395	0.17	-1.7
2,690,421	-		Rv2395	0.17	-0.5
2,690,643	+		Rv2395	0.28	-0.4
2,690,764	-		Rv2395	0.35	-0.9
2,690,811	-		Rv2395	0.37	+0.3
2,690,811	-		Rv2395	0.37	-0.1