Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2292c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
2,563,112	+				-3.5
2,563,297	+		Rv2291	0.14	+2.3
2,563,301	+		Rv2291	0.15	-0.1
2,563,302	-		Rv2291	0.15	-0.1
2,563,326	-		Rv2291	0.18	-0.4
2,563,326	-		Rv2291	0.18	-2.2
2,563,359	+		Rv2291	0.22	+1.3
2,563,359	+		Rv2291	0.22	-0.3
2,563,360	-		Rv2291	0.22	-1.3
2,563,360	-		Rv2291	0.22	+0.3
2,563,401	+		Rv2291	0.27	-0.9
2,564,100	-		Rv2292c	0.32	-1.7
2,564,260	+				-0.3
2,564,322	+				-0.4
2,564,328	+				-0.2
2,564,330	+				-1.3
2,564,330	+				-1.6
2,564,331	-				+0.2
2,564,355	+				-0.1
2,564,356	-				+0.3
2,564,429	+		Rv2293c	0.18	+0.1
2,564,753	+		Rv2293c	0.62	-0.1
2,564,754	-		Rv2293c	0.62	+1.0
2,564,818	+		Rv2293c	0.71	-0.1
2,564,818	+		Rv2293c	0.71	-0.1
2,564,819	-		Rv2293c	0.71	+1.0
2,564,821	+		Rv2293c	0.71	-1.6
2,565,040	+				+0.7
2,565,149	-				+1.9