Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2185c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
2,446,279	+		Rv2184c	0.41	+0.7
2,446,556	-		Rv2184c	0.66	-0.4
2,446,939	-				-1.2
2,446,975	-				+0.5
2,447,109	-				+0.2
2,447,218	-		Rv2185c	0.35	+1.8
2,447,238	-		Rv2185c	0.40	+0.3
2,447,266	+		Rv2185c	0.46	+1.1
2,447,378	+		Rv2185c	0.72	+3.3
2,447,397	+		Rv2185c	0.76	-0.5
2,447,506	+				+0.3
2,447,507	-				-0.4
2,447,507	-				-1.4
2,447,578	+				-1.4
2,447,579	-				-0.7
2,447,606	+				-0.8
2,447,607	-				-0.5
2,448,010	+				-0.8
2,448,011	-				-1.2
2,448,099	+				-0.7
2,448,099	+				+0.5
2,448,262	+				-0.9
2,448,262	+				-0.6
2,448,262	+				-1.2
2,448,263	-				-0.7
2,448,263	-				+1.5
2,448,377	+		Rv2187	0.12	+0.7
2,448,378	-		Rv2187	0.12	+0.3
2,448,401	-		Rv2187	0.13	-0.4
2,448,452	+		Rv2187	0.16	-0.5
2,448,460	+		Rv2187	0.17	-0.6
2,448,461	-		Rv2187	0.17	-1.7
2,448,498	-		Rv2187	0.19	-1.2
2,448,498	-		Rv2187	0.19	-0.3