Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2149c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv2147c and Rv2148c overlap by 4 nucleotidesRv2148c and Rv2149c are separated by 5 nucleotidesRv2149c and Rv2150c are separated by 10 nucleotides Rv2147c: Rv2147c - Conserved hypothetical protein, at 2,406,118 to 2,406,843 Rv2147c Rv2148c: Rv2148c - Conserved protein, at 2,406,840 to 2,407,616 Rv2148c Rv2149c: Rv2149c - Conserved protein YfiH, at 2,407,622 to 2,408,374 Rv2149c Rv2150c: Rv2150c - Cell division protein FtsZ, at 2,408,385 to 2,409,524 Rv2150c Position (kb) 2407 2408 2409Strain fitness (log2 ratio) -1 0 1 2 3at 2407.169 kb on - strand, within Rv2148cat 2407.169 kb on - strand, within Rv2148cat 2407.377 kb on - strand, within Rv2148cat 2407.488 kb on + strand, within Rv2148cat 2407.860 kb on + strand, within Rv2149cat 2407.861 kb on - strand, within Rv2149cat 2407.861 kb on - strand, within Rv2149cat 2408.072 kb on - strand, within Rv2149cat 2408.072 kb on - strand, within Rv2149cat 2408.107 kb on + strand, within Rv2149cat 2408.108 kb on - strand, within Rv2149cat 2408.338 kb on + strandat 2408.362 kb on + strandat 2408.362 kb on + strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL
remove
2,407,169 - Rv2148c 0.42 -1.0
2,407,169 - Rv2148c 0.42 +0.2
2,407,377 - Rv2148c 0.69 +2.3
2,407,488 + Rv2148c 0.83 +1.3
2,407,860 + Rv2149c 0.32 +1.2
2,407,861 - Rv2149c 0.32 -0.0
2,407,861 - Rv2149c 0.32 +1.3
2,408,072 - Rv2149c 0.60 -0.4
2,408,072 - Rv2149c 0.60 -0.5
2,408,107 + Rv2149c 0.64 +3.3
2,408,108 - Rv2149c 0.65 +1.7
2,408,338 + +0.9
2,408,362 + -0.1
2,408,362 + +0.7

Or see this region's nucleotide sequence