Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1910c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1908c and Rv1909c are separated by 37 nucleotidesRv1909c and Rv1910c are separated by 113 nucleotidesRv1910c and Rv1911c are separated by 82 nucleotidesRv1911c and Rv1912c are separated by 99 nucleotides Rv1908c: Rv1908c - Catalase-peroxidase-peroxynitritase T KatG, at 2,153,889 to 2,156,111 Rv1908c Rv1909c: Rv1909c - Ferric uptake regulation protein FurA (fur), at 2,156,149 to 2,156,592 Rv1909c Rv1910c: Rv1910c - Probable exported protein, at 2,156,706 to 2,157,299 Rv1910c Rv1911c: Rv1911c - Probable lipoprotein LppC, at 2,157,382 to 2,157,987 Rv1911c Rv1912c: Rv1912c - Possible oxidoreductase FadB5, at 2,158,087 to 2,159,091 Rv1912c Position (kb) 2156 2157 2158Strain fitness (log2 ratio) -1 0 1 2 3at 2155.819 kb on + strand, within Rv1908cat 2156.037 kb on - strandat 2156.088 kb on - strandat 2156.195 kb on - strand, within Rv1909cat 2156.204 kb on + strand, within Rv1909cat 2156.205 kb on - strand, within Rv1909cat 2156.205 kb on - strand, within Rv1909cat 2156.205 kb on - strand, within Rv1909cat 2156.205 kb on - strand, within Rv1909cat 2156.423 kb on + strand, within Rv1909cat 2156.440 kb on + strand, within Rv1909cat 2156.584 kb on - strandat 2156.595 kb on + strandat 2156.596 kb on - strandat 2156.602 kb on + strandat 2156.602 kb on + strandat 2156.602 kb on + strandat 2156.602 kb on + strandat 2156.602 kb on + strandat 2156.603 kb on - strandat 2156.603 kb on - strandat 2156.603 kb on - strandat 2156.603 kb on - strandat 2156.603 kb on - strandat 2156.716 kb on + strandat 2156.716 kb on + strandat 2156.716 kb on + strandat 2156.717 kb on - strandat 2156.876 kb on - strand, within Rv1910cat 2156.983 kb on + strand, within Rv1910cat 2156.983 kb on + strand, within Rv1910cat 2156.984 kb on - strand, within Rv1910cat 2157.063 kb on - strand, within Rv1910cat 2157.082 kb on + strand, within Rv1910cat 2157.082 kb on + strand, within Rv1910cat 2157.082 kb on + strand, within Rv1910cat 2157.135 kb on + strand, within Rv1910cat 2157.162 kb on - strand, within Rv1910cat 2157.162 kb on - strand, within Rv1910cat 2157.555 kb on - strand, within Rv1911cat 2157.663 kb on - strand, within Rv1911cat 2157.663 kb on - strand, within Rv1911cat 2157.878 kb on + strand, within Rv1911cat 2157.878 kb on + strand, within Rv1911cat 2157.959 kb on - strandat 2158.010 kb on + strandat 2158.010 kb on + strandat 2158.011 kb on - strandat 2158.013 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL
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2,155,819 + Rv1908c 0.87 +0.7
2,156,037 - -0.3
2,156,088 - -1.0
2,156,195 - Rv1909c 0.10 +0.1
2,156,204 + Rv1909c 0.12 -1.3
2,156,205 - Rv1909c 0.13 -0.8
2,156,205 - Rv1909c 0.13 +0.6
2,156,205 - Rv1909c 0.13 -0.4
2,156,205 - Rv1909c 0.13 -0.4
2,156,423 + Rv1909c 0.62 +0.7
2,156,440 + Rv1909c 0.66 +0.3
2,156,584 - -0.1
2,156,595 + +0.8
2,156,596 - -0.2
2,156,602 + -0.2
2,156,602 + +3.3
2,156,602 + +0.5
2,156,602 + -0.8
2,156,602 + -0.4
2,156,603 - -1.1
2,156,603 - -0.5
2,156,603 - +0.4
2,156,603 - -0.3
2,156,603 - +0.7
2,156,716 + -0.6
2,156,716 + +2.3
2,156,716 + +1.3
2,156,717 - -0.5
2,156,876 - Rv1910c 0.29 +0.7
2,156,983 + Rv1910c 0.47 +1.7
2,156,983 + Rv1910c 0.47 +0.2
2,156,984 - Rv1910c 0.47 -0.3
2,157,063 - Rv1910c 0.60 +1.3
2,157,082 + Rv1910c 0.63 -0.4
2,157,082 + Rv1910c 0.63 -0.0
2,157,082 + Rv1910c 0.63 +2.3
2,157,135 + Rv1910c 0.72 -1.0
2,157,162 - Rv1910c 0.77 -0.1
2,157,162 - Rv1910c 0.77 -0.3
2,157,555 - Rv1911c 0.29 -0.5
2,157,663 - Rv1911c 0.46 +0.6
2,157,663 - Rv1911c 0.46 +0.8
2,157,878 + Rv1911c 0.82 -1.7
2,157,878 + Rv1911c 0.82 -0.5
2,157,959 - -0.5
2,158,010 + -0.5
2,158,010 + +0.7
2,158,011 - +2.3
2,158,013 + +0.7

Or see this region's nucleotide sequence