Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1858

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
2,104,890	+				-0.6
2,104,918	-				+0.3
2,104,918	-				+0.3
2,104,967	-				-0.5
2,104,973	+				+0.7
2,104,973	+				-0.5
2,104,974	-				+0.1
2,104,974	-				+1.3
2,105,014	-				-1.5
2,105,516	-		Rv1857	0.68	+0.1
2,105,573	+		Rv1857	0.75	+0.2
2,105,573	+		Rv1857	0.75	-0.4
2,105,573	+		Rv1857	0.75	-1.3
2,105,574	-		Rv1857	0.75	+0.3
2,105,574	-		Rv1857	0.75	-1.4
2,105,651	+		Rv1857	0.85	-0.0
2,105,652	-		Rv1857	0.85	-0.4
2,105,667	+		Rv1857	0.87	-1.4
2,105,668	-		Rv1857	0.87	-1.4
2,105,804	+				-0.5
2,105,804	+				-0.5
2,105,805	-				-0.3
2,105,805	-				-0.9
2,105,806	+				+1.3
2,105,806	+				-1.6
2,105,806	+				-0.1
2,105,902	-		Rv1858	0.16	-0.6
2,106,094	+		Rv1858	0.40	-2.0
2,106,163	-		Rv1858	0.49	-1.0
2,106,221	+		Rv1858	0.56	-0.9
2,106,254	-		Rv1858	0.61	-1.2
2,106,392	+		Rv1858	0.78	-0.6
2,106,446	-		Rv1858	0.85	-0.3
2,106,446	-		Rv1858	0.85	-1.2
2,106,507	-				+0.7
2,106,541	-				-0.2
2,106,703	-		Rv1859	0.12	+1.7
2,106,737	+		Rv1859	0.15	-0.0
2,106,737	+		Rv1859	0.15	-0.2
2,106,737	+		Rv1859	0.15	+1.8
2,106,737	+		Rv1859	0.15	-0.5
2,106,738	-		Rv1859	0.15	+0.3
2,106,738	-		Rv1859	0.15	-1.0
2,106,975	+		Rv1859	0.36	-0.2
2,106,976	-		Rv1859	0.36	+0.2
2,106,989	+		Rv1859	0.37	-0.5
2,106,989	+		Rv1859	0.37	-3.8
2,106,990	-		Rv1859	0.37	-0.7
2,106,990	-		Rv1859	0.37	-0.8
2,107,119	+		Rv1859	0.49	-1.0
2,107,119	+		Rv1859	0.49	+1.7
2,107,119	+		Rv1859	0.49	-0.9
2,107,119	+		Rv1859	0.49	+0.6
2,107,120	-		Rv1859	0.49	-0.9
2,107,120	-		Rv1859	0.49	-0.6
2,107,148	+		Rv1859	0.52	-0.8
2,107,149	-		Rv1859	0.52	+1.0
2,107,254	+		Rv1859	0.61	-0.8
2,107,361	-		Rv1859	0.71	+2.0
2,107,436	-		Rv1859	0.78	-0.6
2,107,467	+		Rv1859	0.80	-0.8
2,107,467	+		Rv1859	0.80	-0.1