Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1628c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1627c and Rv1628c overlap by 4 nucleotidesRv1628c and Rv1629 are separated by 103 nucleotides Rv1627c: Rv1627c - Probable nonspecific lipid-transfer protein, at 1,828,865 to 1,830,073 Rv1627c Rv1628c: Rv1628c - Conserved protein, at 1,830,070 to 1,830,561 Rv1628c Rv1629: Rv1629 - Probable DNA polymerase I PolA, at 1,830,665 to 1,833,379 Rv1629 Position (kb) 1830 1831Strain fitness (log2 ratio) -2 -1 0 1 2at 1829.169 kb on + strand, within Rv1627cat 1829.170 kb on - strand, within Rv1627cat 1829.186 kb on + strand, within Rv1627cat 1829.187 kb on - strand, within Rv1627cat 1829.534 kb on + strand, within Rv1627cat 1829.593 kb on - strand, within Rv1627cat 1829.593 kb on - strand, within Rv1627cat 1829.820 kb on + strand, within Rv1627cat 1829.821 kb on - strand, within Rv1627cat 1830.004 kb on + strandat 1830.005 kb on - strandat 1830.028 kb on + strandat 1830.045 kb on + strandat 1830.046 kb on - strandat 1830.046 kb on - strandat 1830.397 kb on + strand, within Rv1628cat 1830.397 kb on + strand, within Rv1628cat 1830.398 kb on - strand, within Rv1628cat 1830.455 kb on + strand, within Rv1628cat 1830.508 kb on - strand, within Rv1628cat 1830.508 kb on - strand, within Rv1628cat 1830.652 kb on + strandat 1830.653 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL
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1,829,169 + Rv1627c 0.25 +0.5
1,829,170 - Rv1627c 0.25 -0.2
1,829,186 + Rv1627c 0.27 -1.4
1,829,187 - Rv1627c 0.27 -0.9
1,829,534 + Rv1627c 0.55 -0.0
1,829,593 - Rv1627c 0.60 +0.4
1,829,593 - Rv1627c 0.60 -1.0
1,829,820 + Rv1627c 0.79 -1.6
1,829,821 - Rv1627c 0.79 -0.6
1,830,004 + -1.3
1,830,005 - -0.3
1,830,028 + -2.4
1,830,045 + +1.3
1,830,046 - -0.8
1,830,046 - +0.4
1,830,397 + Rv1628c 0.66 +0.5
1,830,397 + Rv1628c 0.66 +1.6
1,830,398 - Rv1628c 0.67 -1.0
1,830,455 + Rv1628c 0.78 -0.5
1,830,508 - Rv1628c 0.89 -0.3
1,830,508 - Rv1628c 0.89 +1.9
1,830,652 + -0.4
1,830,653 - -1.0

Or see this region's nucleotide sequence