Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1608c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1607 and Rv1608c are separated by 34 nucleotidesRv1608c and Rv1609 are separated by 140 nucleotides Rv1607: Rv1607 - Probable ionic transporter integral membrane protein ChaA, at 1,806,181 to 1,807,263 Rv1607 Rv1608c: Rv1608c - Probable peroxidoxin BcpB, at 1,807,298 to 1,807,762 Rv1608c Rv1609: Rv1609 - Anthranilate synthase component I TrpE (glutamine amidotransferase), at 1,807,903 to 1,809,453 Rv1609 Position (kb) 1807 1808Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1806.703 kb on + strand, within Rv1607at 1806.703 kb on + strand, within Rv1607at 1806.704 kb on - strand, within Rv1607at 1807.033 kb on + strand, within Rv1607at 1807.033 kb on + strand, within Rv1607at 1807.033 kb on + strand, within Rv1607at 1807.033 kb on + strand, within Rv1607at 1807.034 kb on - strand, within Rv1607at 1807.053 kb on + strand, within Rv1607at 1807.237 kb on + strandat 1807.238 kb on - strandat 1807.387 kb on + strand, within Rv1608cat 1807.387 kb on + strand, within Rv1608cat 1807.388 kb on - strand, within Rv1608cat 1807.388 kb on - strand, within Rv1608cat 1807.388 kb on - strand, within Rv1608cat 1807.656 kb on + strand, within Rv1608cat 1807.656 kb on + strand, within Rv1608cat 1807.774 kb on + strandat 1807.774 kb on + strandat 1807.775 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL
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1,806,703 + Rv1607 0.48 -0.4
1,806,703 + Rv1607 0.48 +0.1
1,806,704 - Rv1607 0.48 -2.3
1,807,033 + Rv1607 0.79 +1.3
1,807,033 + Rv1607 0.79 -0.3
1,807,033 + Rv1607 0.79 +0.3
1,807,033 + Rv1607 0.79 +0.3
1,807,034 - Rv1607 0.79 -1.4
1,807,053 + Rv1607 0.81 -1.2
1,807,237 + -1.0
1,807,238 - -0.4
1,807,387 + Rv1608c 0.19 -0.1
1,807,387 + Rv1608c 0.19 +0.2
1,807,388 - Rv1608c 0.19 +2.8
1,807,388 - Rv1608c 0.19 +1.9
1,807,388 - Rv1608c 0.19 +2.3
1,807,656 + Rv1608c 0.77 +2.9
1,807,656 + Rv1608c 0.77 -0.4
1,807,774 + +2.6
1,807,774 + -0.9
1,807,775 - -1.3

Or see this region's nucleotide sequence