Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1345

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
1,508,586	-		Rv1343c	0.11	-1.4
1,508,985	-				-0.0
1,509,020	+		Rv1344	0.16	-0.9
1,509,021	-		Rv1344	0.17	-1.1
1,509,021	-		Rv1344	0.17	-0.7
1,509,063	+		Rv1344	0.30	-1.2
1,509,391	-				-1.6
1,509,426	+				+0.5
1,509,544	-		Rv1345	0.17	-0.2
1,509,616	-		Rv1345	0.21	-0.8
1,509,616	-		Rv1345	0.21	+0.9
1,509,632	+		Rv1345	0.22	-0.5
1,509,633	-		Rv1345	0.22	+0.0
1,509,659	-		Rv1345	0.24	-1.4
1,509,880	-		Rv1345	0.38	-1.1
1,510,061	+		Rv1345	0.50	-0.7
1,510,062	-		Rv1345	0.50	-0.1
1,510,205	+		Rv1345	0.59	-0.9
1,510,297	+		Rv1345	0.65	-0.5
1,510,338	+		Rv1345	0.67	-0.8
1,510,339	-		Rv1345	0.68	-1.5
1,510,991	+		Rv1346	0.12	-1.1
1,511,146	+		Rv1346	0.26	+0.7
1,511,252	+		Rv1346	0.35	-1.1
1,511,253	-		Rv1346	0.35	-1.7
1,511,368	-		Rv1346	0.45	-0.7
1,511,682	+		Rv1346	0.72	-0.5