Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0953c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0951 and Rv0952 are separated by 12 nucleotidesRv0952 and Rv0953c are separated by 62 nucleotidesRv0953c and Rv0954 are separated by 164 nucleotides Rv0951: Rv0951 - Probable succinyl-CoA synthetase (beta chain) SucC (SCS-beta), at 1,061,964 to 1,063,127 Rv0951 Rv0952: Rv0952 - Probable succinyl-CoA synthetase (alpha chain) SucD (SCS-alpha), at 1,063,140 to 1,064,051 Rv0952 Rv0953c: Rv0953c - Possible oxidoreductase, at 1,064,114 to 1,064,962 Rv0953c Rv0954: Rv0954 - Probable conserved transmembrane protein, at 1,065,127 to 1,066,038 Rv0954 Position (kb) 1064 1065Strain fitness (log2 ratio) -2 -1 0 1 2at 1064.067 kb on - strandat 1064.067 kb on - strandat 1064.067 kb on - strandat 1064.154 kb on + strandat 1064.155 kb on - strandat 1064.207 kb on - strand, within Rv0953cat 1064.315 kb on + strand, within Rv0953cat 1064.493 kb on + strand, within Rv0953cat 1064.493 kb on + strand, within Rv0953cat 1064.494 kb on - strand, within Rv0953cat 1064.494 kb on - strand, within Rv0953cat 1064.538 kb on + strand, within Rv0953cat 1064.784 kb on + strand, within Rv0953cat 1065.233 kb on + strand, within Rv0954at 1065.234 kb on - strand, within Rv0954at 1065.281 kb on - strand, within Rv0954at 1065.440 kb on + strand, within Rv0954at 1065.440 kb on + strand, within Rv0954at 1065.646 kb on + strand, within Rv0954at 1065.697 kb on + strand, within Rv0954at 1065.698 kb on - strand, within Rv0954

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL
remove
1,064,067 - -0.7
1,064,067 - -1.2
1,064,067 - -1.8
1,064,154 + +2.2
1,064,155 - -1.1
1,064,207 - Rv0953c 0.11 -0.7
1,064,315 + Rv0953c 0.24 -0.6
1,064,493 + Rv0953c 0.45 +1.8
1,064,493 + Rv0953c 0.45 +0.5
1,064,494 - Rv0953c 0.45 -0.3
1,064,494 - Rv0953c 0.45 +0.8
1,064,538 + Rv0953c 0.50 +0.5
1,064,784 + Rv0953c 0.79 -0.7
1,065,233 + Rv0954 0.12 +0.2
1,065,234 - Rv0954 0.12 -0.4
1,065,281 - Rv0954 0.17 -1.2
1,065,440 + Rv0954 0.34 +1.4
1,065,440 + Rv0954 0.34 -1.1
1,065,646 + Rv0954 0.57 +0.2
1,065,697 + Rv0954 0.62 -2.3
1,065,698 - Rv0954 0.63 +0.2

Or see this region's nucleotide sequence