Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0869c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0867c and Rv0868c are separated by 447 nucleotidesRv0868c and Rv0869c are separated by 3 nucleotidesRv0869c and Rv0870c overlap by 4 nucleotidesRv0870c and Rv0871 are separated by 164 nucleotides Rv0867c: Rv0867c - Possible resuscitation-promoting factor RpfA, at 964,312 to 965,535 Rv0867c Rv0868c: Rv0868c - Probable molybdenum cofactor biosynthesis protein D 2 MoaD2 (molybdopterin converting factor small subunit) (molybdopterin [MPT] converting factor, subunit 1), at 965,983 to 966,261 Rv0868c Rv0869c: Rv0869c - Probable molybdenum cofactor biosynthesis protein A2 MoaA2, at 966,265 to 967,347 Rv0869c Rv0870c: Rv0870c - Possible conserved integral membrane protein, at 967,344 to 967,733 Rv0870c Rv0871: Rv0871 - Probable cold shock-like protein B CspB, at 967,898 to 968,305 Rv0871 Position (kb) 966 967 968Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3 4at 965.345 kb on + strand, within Rv0867cat 965.465 kb on - strandat 965.517 kb on + strandat 965.517 kb on + strandat 965.518 kb on - strandat 965.518 kb on - strandat 965.535 kb on + strandat 965.536 kb on - strandat 965.536 kb on - strandat 965.536 kb on - strandat 965.536 kb on - strandat 965.540 kb on + strandat 965.544 kb on + strandat 965.629 kb on - strandat 965.629 kb on - strandat 965.629 kb on - strandat 965.668 kb on - strandat 965.668 kb on - strandat 965.845 kb on + strandat 966.004 kb on + strandat 966.005 kb on - strandat 966.005 kb on - strandat 966.005 kb on - strandat 966.007 kb on + strandat 966.007 kb on + strandat 966.007 kb on + strandat 966.074 kb on + strand, within Rv0868cat 966.074 kb on + strand, within Rv0868cat 966.212 kb on + strand, within Rv0868cat 966.673 kb on - strand, within Rv0869cat 966.717 kb on - strand, within Rv0869cat 966.871 kb on - strand, within Rv0869cat 966.871 kb on - strand, within Rv0869cat 966.898 kb on - strand, within Rv0869cat 967.008 kb on + strand, within Rv0869cat 967.008 kb on + strand, within Rv0869cat 967.008 kb on + strand, within Rv0869cat 967.009 kb on - strand, within Rv0869cat 967.009 kb on - strand, within Rv0869cat 967.009 kb on - strand, within Rv0869cat 967.109 kb on - strand, within Rv0869cat 967.109 kb on - strand, within Rv0869cat 967.184 kb on + strand, within Rv0869cat 967.184 kb on + strand, within Rv0869cat 967.185 kb on - strand, within Rv0869cat 967.276 kb on + strandat 967.431 kb on + strand, within Rv0870cat 967.673 kb on - strand, within Rv0870cat 967.673 kb on - strand, within Rv0870cat 967.713 kb on - strandat 967.748 kb on + strandat 967.773 kb on + strandat 967.774 kb on - strandat 967.806 kb on + strandat 967.807 kb on - strandat 967.923 kb on - strandat 967.923 kb on - strandat 967.977 kb on - strand, within Rv0871at 967.977 kb on - strand, within Rv0871

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL
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965,345 + Rv0867c 0.84 -0.9
965,465 - -0.7
965,517 + -0.2
965,517 + -1.1
965,518 - +0.3
965,518 - -0.5
965,535 + -0.2
965,536 - -0.3
965,536 - -0.7
965,536 - -0.7
965,536 - -0.3
965,540 + -0.1
965,544 + +0.6
965,629 - -1.1
965,629 - +0.7
965,629 - -1.7
965,668 - -0.7
965,668 - -0.5
965,845 + -0.2
966,004 + +1.3
966,005 - -0.4
966,005 - -2.2
966,005 - -1.2
966,007 + -1.0
966,007 + -0.4
966,007 + +2.3
966,074 + Rv0868c 0.33 +1.0
966,074 + Rv0868c 0.33 -0.0
966,212 + Rv0868c 0.82 -1.0
966,673 - Rv0869c 0.38 -0.4
966,717 - Rv0869c 0.42 -1.5
966,871 - Rv0869c 0.56 -0.5
966,871 - Rv0869c 0.56 -1.6
966,898 - Rv0869c 0.58 -3.4
967,008 + Rv0869c 0.69 -1.3
967,008 + Rv0869c 0.69 -0.5
967,008 + Rv0869c 0.69 -0.8
967,009 - Rv0869c 0.69 -0.6
967,009 - Rv0869c 0.69 +0.7
967,009 - Rv0869c 0.69 -1.0
967,109 - Rv0869c 0.78 -0.7
967,109 - Rv0869c 0.78 -0.8
967,184 + Rv0869c 0.85 -0.2
967,184 + Rv0869c 0.85 -0.6
967,185 - Rv0869c 0.85 +4.6
967,276 + +0.3
967,431 + Rv0870c 0.22 -1.5
967,673 - Rv0870c 0.84 -0.8
967,673 - Rv0870c 0.84 -0.9
967,713 - -0.6
967,748 + -1.2
967,773 + -0.8
967,774 - -0.5
967,806 + -0.4
967,807 - -0.6
967,923 - -1.7
967,923 - -0.9
967,977 - Rv0871 0.19 -1.2
967,977 - Rv0871 0.19 -2.6

Or see this region's nucleotide sequence