Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0583c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0580c and Rv0581 are separated by 93 nucleotidesRv0581 and Rv0582 overlap by 4 nucleotidesRv0582 and Rv0583c are separated by 59 nucleotidesRv0583c and Rv0584 are separated by 153 nucleotides Rv0580c: Rv0580c - Conserved protein, at 677,125 to 677,616 Rv0580c Rv0581: Rv0581 - Possible antitoxin VapB26, at 677,710 to 677,925 Rv0581 Rv0582: Rv0582 - Possible toxin VapC26. Contains PIN domain., at 677,922 to 678,329 Rv0582 Rv0583c: Rv0583c - Probable conserved lipoprotein LpqN, at 678,389 to 679,075 Rv0583c Rv0584: Rv0584 - Possible conserved exported protein, at 679,229 to 681,862 Rv0584 Position (kb) 678 679 680Strain fitness (log2 ratio) -2 -1 0 1 2 3at 677.627 kb on + strandat 677.680 kb on - strandat 677.859 kb on - strand, within Rv0581at 677.859 kb on - strand, within Rv0581at 677.861 kb on - strand, within Rv0581at 678.555 kb on + strand, within Rv0583cat 678.555 kb on + strand, within Rv0583cat 678.766 kb on - strand, within Rv0583cat 678.885 kb on + strand, within Rv0583cat 678.886 kb on - strand, within Rv0583cat 678.900 kb on + strand, within Rv0583cat 678.901 kb on - strand, within Rv0583cat 678.940 kb on + strand, within Rv0583cat 678.941 kb on - strand, within Rv0583cat 679.210 kb on + strandat 679.218 kb on - strandat 679.319 kb on + strandat 679.479 kb on - strandat 679.487 kb on + strandat 679.488 kb on - strandat 679.488 kb on - strandat 679.494 kb on - strand, within Rv0584at 679.658 kb on + strand, within Rv0584at 679.659 kb on - strand, within Rv0584at 679.662 kb on - strand, within Rv0584at 679.662 kb on - strand, within Rv0584at 679.669 kb on - strand, within Rv0584at 679.802 kb on + strand, within Rv0584at 679.803 kb on - strand, within Rv0584at 679.803 kb on - strand, within Rv0584at 679.803 kb on - strand, within Rv0584at 679.886 kb on + strand, within Rv0584at 679.931 kb on + strand, within Rv0584at 680.051 kb on + strand, within Rv0584at 680.051 kb on + strand, within Rv0584at 680.051 kb on + strand, within Rv0584at 680.052 kb on - strand, within Rv0584

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL
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677,627 + +0.1
677,680 - -0.8
677,859 - Rv0581 0.69 -0.5
677,859 - Rv0581 0.69 +0.1
677,861 - Rv0581 0.70 +1.3
678,555 + Rv0583c 0.24 +0.1
678,555 + Rv0583c 0.24 +0.1
678,766 - Rv0583c 0.55 +1.3
678,885 + Rv0583c 0.72 +3.3
678,886 - Rv0583c 0.72 +0.5
678,900 + Rv0583c 0.74 +0.2
678,901 - Rv0583c 0.75 -1.2
678,940 + Rv0583c 0.80 +0.3
678,941 - Rv0583c 0.80 +2.3
679,210 + +0.2
679,218 - -0.9
679,319 + +0.7
679,479 - +2.6
679,487 + -1.7
679,488 - -0.0
679,488 - -0.9
679,494 - Rv0584 0.10 -1.1
679,658 + Rv0584 0.16 -0.6
679,659 - Rv0584 0.16 -2.0
679,662 - Rv0584 0.16 -1.0
679,662 - Rv0584 0.16 +3.0
679,669 - Rv0584 0.17 -1.4
679,802 + Rv0584 0.22 -1.2
679,803 - Rv0584 0.22 -0.5
679,803 - Rv0584 0.22 +0.1
679,803 - Rv0584 0.22 -0.5
679,886 + Rv0584 0.25 -1.8
679,931 + Rv0584 0.27 +2.3
680,051 + Rv0584 0.31 +0.9
680,051 + Rv0584 0.31 +1.6
680,051 + Rv0584 0.31 -0.5
680,052 - Rv0584 0.31 -1.1

Or see this region's nucleotide sequence