Experiment: 7H9 with Ethionamide 0.1 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0494 and Rv0495c are separated by 0 nucleotides Rv0495c and Rv0496 are separated by 79 nucleotides Rv0496 and Rv0497 overlap by 4 nucleotides Rv0497 and Rv0498 are separated by 15 nucleotides
Rv0494: Rv0494 - Probable transcriptional regulatory protein (probably GntR-family), at 584,695 to 585,423
Rv0494
Rv0495c: Rv0495c - Conserved hypothetical protein, at 585,424 to 586,314
Rv0495c
Rv0496: Rv0496 - Conserved hypothetical protein, at 586,394 to 587,380
Rv0496
Rv0497: Rv0497 - Probable conserved transmembrane protein, at 587,377 to 588,309
Rv0497
Rv0498: Rv0498 - Conserved hypothetical protein, at 588,325 to 589,167
Rv0498
Position (kb) 586
587
588 Strain fitness (log2 ratio) -2
-1
0
1 at 585.422 kb on - strand at 585.422 kb on - strand at 585.422 kb on - strand at 585.426 kb on - strand at 585.426 kb on - strand at 587.001 kb on + strand, within Rv0496 at 587.049 kb on + strand, within Rv0496 at 587.084 kb on - strand, within Rv0496 at 587.084 kb on - strand, within Rv0496 at 587.090 kb on - strand, within Rv0496 at 587.199 kb on + strand, within Rv0496 at 587.200 kb on - strand, within Rv0496 at 588.155 kb on + strand, within Rv0497 at 588.155 kb on + strand, within Rv0497 at 588.164 kb on + strand, within Rv0497 at 588.170 kb on + strand, within Rv0497
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL remove 585,422 - -0.8 585,422 - +0.6 585,422 - +1.5 585,426 - -0.8 585,426 - -0.8 587,001 + Rv0496 0.61 -2.3 587,049 + Rv0496 0.66 -1.7 587,084 - Rv0496 0.70 +0.5 587,084 - Rv0496 0.70 +0.0 587,090 - Rv0496 0.71 +0.7 587,199 + Rv0496 0.82 +1.6 587,200 - Rv0496 0.82 -0.0 588,155 + Rv0497 0.83 -0.2 588,155 + Rv0497 0.83 -2.2 588,164 + Rv0497 0.84 +0.3 588,170 + Rv0497 0.85 +1.7
Or see this region's nucleotide sequence