Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0147

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
172,399	-		Rv0146	0.20	+0.5
172,487	-		Rv0146	0.30	+1.1
172,487	-		Rv0146	0.30	-0.8
172,490	+		Rv0146	0.30	-1.2
172,490	+		Rv0146	0.30	+0.2
172,491	-		Rv0146	0.30	-0.8
172,527	+		Rv0146	0.34	+0.3
172,595	+		Rv0146	0.41	-0.5
172,596	-		Rv0146	0.41	-0.2
172,625	+		Rv0146	0.44	-1.2
172,625	+		Rv0146	0.44	+1.7
172,625	+		Rv0146	0.44	-1.9
172,625	+		Rv0146	0.44	-0.6
172,626	-		Rv0146	0.44	-0.8
172,626	-		Rv0146	0.44	-1.2
172,781	+		Rv0146	0.61	+0.7
172,781	+		Rv0146	0.61	+1.3
172,781	+		Rv0146	0.61	-0.0
172,782	-		Rv0146	0.61	-1.3
172,782	-		Rv0146	0.61	-0.4
172,782	-		Rv0146	0.61	-1.4
172,784	-		Rv0146	0.61	-1.4
172,785	+		Rv0146	0.62	-2.3
172,970	+		Rv0146	0.81	+0.2
172,971	-		Rv0146	0.81	-0.3
172,971	-		Rv0146	0.81	-2.0
173,141	+				-1.3
173,141	+				-0.3
173,142	-				-0.4
173,164	+				+0.2
173,164	+				+1.2
173,164	+				+0.2
173,164	+				-0.8
173,164	+				+1.3
173,164	+				+0.2
173,164	+				+2.3
173,164	+				-2.7
173,164	+				-0.5
173,165	-				-0.3
173,165	-				-0.3
173,165	-				-0.4
173,165	-				-0.8
173,165	-				+0.2
173,165	-				+2.0
173,165	-				-1.6
173,165	-				-3.9
173,166	+				-2.9
173,166	+				-0.8
173,167	-				-1.0
173,167	-				-0.8
173,167	-				-1.0
173,168	+				+0.2
173,177	-				+3.3
173,177	-				-0.1
173,177	-				+0.5
173,177	-				-0.1
173,177	-				+1.3
173,177	-				-0.7
173,178	+				+1.3
173,179	-				-0.5
173,179	-				-0.3
173,179	-				+3.3
173,179	-				-1.5
173,195	+				-0.3
173,196	-				-0.2
173,196	-				-1.0
173,196	-				-2.6
173,219	-				-0.3
173,219	-				+0.6
173,385	-				-0.2
173,548	-		Rv0147	0.20	-0.3
173,548	-		Rv0147	0.20	-1.6
173,586	+		Rv0147	0.23	+0.7
173,626	-		Rv0147	0.26	+0.0
173,673	+		Rv0147	0.29	-0.8
173,674	-		Rv0147	0.29	+0.7
173,695	+		Rv0147	0.30	-0.9
173,696	-		Rv0147	0.30	-0.0
173,696	-		Rv0147	0.30	+0.2
173,696	-		Rv0147	0.30	+0.2
173,724	+		Rv0147	0.32	+1.3
173,832	+		Rv0147	0.39	+0.9
173,832	+		Rv0147	0.39	-0.3
173,832	+		Rv0147	0.39	-0.6
173,832	+		Rv0147	0.39	+0.7
173,832	+		Rv0147	0.39	-0.7
173,833	-		Rv0147	0.39	-0.2
173,838	+		Rv0147	0.39	+1.4
173,839	-		Rv0147	0.40	-0.3
173,958	+		Rv0147	0.47	+0.4
173,958	+		Rv0147	0.47	+0.4
173,959	-		Rv0147	0.47	+0.6
174,043	+		Rv0147	0.53	-0.8
174,043	+		Rv0147	0.53	-0.5
174,043	+		Rv0147	0.53	-0.0
174,044	-		Rv0147	0.53	+0.8
174,044	-		Rv0147	0.53	+0.6
174,044	-		Rv0147	0.53	+0.0
174,115	-		Rv0147	0.58	-0.6
174,115	-		Rv0147	0.58	-1.5
174,488	+		Rv0147	0.82	-0.2
174,489	-		Rv0147	0.82	+1.3
174,659	+				+0.3
174,659	+				-0.3
174,660	-				+0.0
174,798	+				-2.1
174,798	+				-1.2
174,799	-				+0.3
174,799	-				+1.0
174,896	+				-0.7
175,192	+		Rv0148	0.42	-0.3
175,205	+		Rv0148	0.43	-0.4
175,214	+		Rv0148	0.44	-0.1
175,224	+		Rv0148	0.45	-1.4
175,225	-		Rv0148	0.46	+1.0
175,246	-		Rv0148	0.48	-0.3
175,322	+		Rv0148	0.57	+1.9
175,323	-		Rv0148	0.57	-0.7
175,323	-		Rv0148	0.57	+0.7
175,323	-		Rv0148	0.57	-1.8
175,323	-		Rv0148	0.57	+0.1
175,323	-		Rv0148	0.57	-0.3
175,323	-		Rv0148	0.57	-0.2
175,386	-		Rv0148	0.64	+1.8
175,386	-		Rv0148	0.64	-0.4
175,386	-		Rv0148	0.64	-2.5
175,502	+		Rv0148	0.78	-0.7
175,502	+		Rv0148	0.78	+1.7
175,620	+				-0.5
175,621	-				+0.2
175,692	-				+0.3
175,697	+				-0.3
175,717	-				-1.0
175,748	+				-1.0