Experiment: 7H9 with Ethionamide 0.1 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0041 and Rv0042c are separated by 109 nucleotides Rv0042c and Rv0043c are separated by 158 nucleotides Rv0043c and Rv0044c are separated by 132 nucleotides Rv0044c and Rv0045c are separated by 15 nucleotides
Rv0041: Rv0041 - Probable leucyl-tRNA synthetase LeuS (leucine--tRNA ligase) (LEURS), at 43,562 to 46,471
Rv0041
Rv0042c: Rv0042c - Possible transcriptional regulatory protein (probably MarR-family), at 46,581 to 47,207
Rv0042c
Rv0043c: Rv0043c - Probable transcriptional regulatory protein (probably GntR-family), at 47,366 to 48,100
Rv0043c
Rv0044c: Rv0044c - Possible oxidoreductase, at 48,233 to 49,027
Rv0044c
Rv0045c: Rv0045c - Possible hydrolase, at 49,043 to 49,939
Rv0045c
Position (kb) 47
48
49 Strain fitness (log2 ratio) -1
0
1 at 46.470 kb on - strand at 46.526 kb on - strand at 47.367 kb on + strand at 47.610 kb on + strand, within Rv0043c at 47.611 kb on - strand, within Rv0043c at 48.038 kb on + strand at 48.104 kb on + strand at 48.105 kb on - strand at 48.105 kb on - strand at 48.108 kb on + strand at 48.108 kb on + strand at 48.109 kb on - strand at 48.109 kb on - strand at 48.446 kb on + strand, within Rv0044c at 48.451 kb on - strand, within Rv0044c at 48.490 kb on - strand, within Rv0044c at 48.514 kb on + strand, within Rv0044c at 48.514 kb on + strand, within Rv0044c at 48.515 kb on - strand, within Rv0044c at 48.731 kb on - strand, within Rv0044c at 48.766 kb on - strand, within Rv0044c at 48.766 kb on - strand, within Rv0044c at 48.783 kb on - strand, within Rv0044c at 48.896 kb on - strand, within Rv0044c at 48.954 kb on + strand at 48.983 kb on + strand at 48.984 kb on - strand at 48.984 kb on - strand at 48.992 kb on - strand at 49.039 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL remove 46,470 - +0.6 46,526 - -1.1 47,367 + -1.4 47,610 + Rv0043c 0.33 +0.6 47,611 - Rv0043c 0.33 +0.3 48,038 + +0.8 48,104 + +1.5 48,105 - -1.1 48,105 - +0.0 48,108 + -0.7 48,108 + +0.5 48,109 - +0.1 48,109 - +0.5 48,446 + Rv0044c 0.27 -0.5 48,451 - Rv0044c 0.27 -1.2 48,490 - Rv0044c 0.32 -0.5 48,514 + Rv0044c 0.35 -0.2 48,514 + Rv0044c 0.35 -0.7 48,515 - Rv0044c 0.35 +0.5 48,731 - Rv0044c 0.63 -0.6 48,766 - Rv0044c 0.67 -1.4 48,766 - Rv0044c 0.67 -0.9 48,783 - Rv0044c 0.69 -1.7 48,896 - Rv0044c 0.83 -1.7 48,954 + +1.3 48,983 + -0.9 48,984 - -1.5 48,984 - -0.8 48,992 - -0.4 49,039 - -0.2
Or see this region's nucleotide sequence