Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3553

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
3,990,713	-				-0.2
3,990,716	+				+0.1
3,991,290	+		Rv3552	0.69	+0.4
3,991,310	-		Rv3552	0.72	-1.0
3,991,480	+				+0.5
3,991,621	-				-0.4
3,992,183	-		Rv3553	0.53	-1.2
3,992,607	-				-1.2
3,992,607	-				+0.3
3,992,660	+				+0.2
3,992,709	+				-2.3
3,992,723	+				-0.9
3,992,723	+				-0.9
3,992,723	+				-0.1
3,992,724	-				-1.4
3,992,724	-				-0.6
3,992,864	+				+1.1
3,992,864	+				-0.4
3,992,874	+				-0.6
3,993,060	+		Rv3554	0.18	-0.9
3,993,060	+		Rv3554	0.18	-0.9
3,993,177	+		Rv3554	0.24	-1.4
3,993,178	-		Rv3554	0.24	+0.1
3,993,186	+		Rv3554	0.24	-0.2
3,993,186	+		Rv3554	0.24	-1.6
3,993,332	+		Rv3554	0.31	+0.6
3,993,411	+		Rv3554	0.35	-1.5
3,993,555	+		Rv3554	0.42	+1.5
3,993,556	-		Rv3554	0.42	-0.1
3,993,556	-		Rv3554	0.42	+0.5
3,993,556	-		Rv3554	0.42	-0.0