Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3545c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
3,983,211	-				-0.8
3,983,214	-				+0.5
3,983,403	-		Rv3544c	0.27	-0.0
3,983,403	-		Rv3544c	0.27	-2.9
3,983,477	+		Rv3544c	0.35	-0.7
3,983,523	-		Rv3544c	0.39	+0.5
3,983,523	-		Rv3544c	0.39	-0.5
3,983,652	+		Rv3544c	0.52	+1.3
3,983,653	-		Rv3544c	0.52	-0.3
3,983,995	+		Rv3544c	0.85	-0.6
3,984,146	-				+0.3
3,984,164	+				-0.7
3,984,165	-				+2.6
3,984,172	+				-1.6
3,984,173	-				+1.5
3,984,191	+				-0.6
3,984,279	+		Rv3545c	0.10	+0.9
3,984,280	-		Rv3545c	0.10	-0.9
3,984,319	+		Rv3545c	0.13	+0.7
3,984,320	-		Rv3545c	0.14	-1.7
3,984,374	+		Rv3545c	0.18	-2.1
3,984,374	+		Rv3545c	0.18	-1.2
3,984,375	-		Rv3545c	0.18	+1.1
3,984,452	+		Rv3545c	0.24	-0.0
3,984,452	+		Rv3545c	0.24	-0.4
3,984,565	+		Rv3545c	0.32	-0.3
3,984,565	+		Rv3545c	0.32	-0.3
3,984,565	+		Rv3545c	0.32	-1.1
3,984,566	-		Rv3545c	0.32	-1.0
3,984,823	+		Rv3545c	0.52	-0.9
3,984,823	+		Rv3545c	0.52	+0.2
3,985,172	-		Rv3545c	0.79	-1.1
3,985,401	-				+0.7
3,985,410	+				-0.4
3,985,411	-				-0.3
3,985,411	-				-1.4
3,985,527	+				+1.0
3,986,412	+		Rv3546	0.73	-0.6
3,986,412	+		Rv3546	0.73	-0.6
3,986,413	-		Rv3546	0.73	-1.2