Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3536c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
3,973,583	+				+0.1
3,973,604	+				-1.2
3,973,605	-				-0.8
3,973,803	+		Rv3535c	0.23	+0.2
3,973,804	-		Rv3535c	0.24	-1.1
3,973,804	-		Rv3535c	0.24	-2.6
3,974,238	+		Rv3535c	0.71	-0.2
3,974,265	+		Rv3535c	0.74	-1.0
3,974,300	-		Rv3535c	0.78	+0.3
3,974,300	-		Rv3535c	0.78	+1.3
3,974,459	-				+1.2
3,975,058	+		Rv3536c	0.70	-0.9
3,975,058	+		Rv3536c	0.70	+2.7
3,975,058	+		Rv3536c	0.70	-0.7
3,975,116	+		Rv3536c	0.77	-0.9
3,975,116	+		Rv3536c	0.77	-1.6
3,975,116	+		Rv3536c	0.77	+1.8
3,975,117	-		Rv3536c	0.77	+0.4
3,975,256	-				-0.5
3,975,487	-				-0.9
3,975,566	+		Rv3537	0.12	+1.5
3,975,588	+		Rv3537	0.13	+0.7
3,975,588	+		Rv3537	0.13	+2.1
3,975,639	+		Rv3537	0.16	-0.6
3,975,724	-		Rv3537	0.21	-0.3
3,975,724	-		Rv3537	0.21	+0.6
3,975,871	-		Rv3537	0.30	-2.3
3,975,871	-		Rv3537	0.30	-0.9