Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3324c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3322c and Rv3323c overlap by 4 nucleotidesRv3323c and Rv3324c are separated by 0 nucleotidesRv3324c and Rv3324A overlap by 4 nucleotidesRv3324A and Rv3325 are separated by 53 nucleotidesRv3325 and Rv3326 overlap by 52 nucleotides Rv3322c: Rv3322c - Possible methyltransferase, at 3,708,438 to 3,709,052 Rv3322c Rv3323c: Rv3323c - Probable MoaD-MoaE fusion protein MoaX, at 3,709,049 to 3,709,714 Rv3323c Rv3324c: Rv3324c - Probable molybdenum cofactor biosynthesis protein C 3 MoaC3, at 3,709,715 to 3,710,248 Rv3324c Rv3324A: Rv3324A - Probable fragment of pterin-4-alpha-carbinolamine dehydratase MOAB3 (PHS) (4-alpha-hydroxy-tetrahydropterin dehydratase) (pterin-4-a-carbinolamine dehydratase) (phenylalanine hydroxylase-stimulating protein) (PHS) (pterin carbinolamine dehydratase) (PCD), at 3,710,245 to 3,710,379 Rv3324A Rv3325: Rv3325 - Probable transposase for insertion sequence element IS6110 (fragment), at 3,710,433 to 3,710,759 Rv3325 Rv3326: Rv3326 - Probable transposase, at 3,710,708 to 3,711,694 Rv3326 Position (kb) 3709 3710 3711Strain fitness (log2 ratio) -1 0 1 2at 3709.320 kb on + strand, within Rv3323cat 3709.320 kb on + strand, within Rv3323cat 3709.321 kb on - strand, within Rv3323cat 3709.321 kb on - strand, within Rv3323cat 3709.323 kb on + strand, within Rv3323cat 3709.323 kb on + strand, within Rv3323cat 3709.324 kb on - strand, within Rv3323cat 3709.357 kb on + strand, within Rv3323cat 3709.357 kb on + strand, within Rv3323cat 3709.458 kb on + strand, within Rv3323cat 3709.459 kb on - strand, within Rv3323cat 3709.487 kb on + strand, within Rv3323cat 3709.487 kb on + strand, within Rv3323cat 3709.693 kb on - strandat 3709.709 kb on - strandat 3709.915 kb on + strand, within Rv3324cat 3709.915 kb on + strand, within Rv3324cat 3709.915 kb on + strand, within Rv3324cat 3709.915 kb on + strand, within Rv3324cat 3709.915 kb on + strand, within Rv3324cat 3709.916 kb on - strand, within Rv3324cat 3709.916 kb on - strand, within Rv3324cat 3709.916 kb on - strand, within Rv3324cat 3710.048 kb on - strand, within Rv3324cat 3710.072 kb on + strand, within Rv3324cat 3710.072 kb on + strand, within Rv3324cat 3710.073 kb on - strand, within Rv3324cat 3710.224 kb on + strandat 3710.224 kb on + strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL
remove
3,709,320 + Rv3323c 0.41 +1.1
3,709,320 + Rv3323c 0.41 +2.1
3,709,321 - Rv3323c 0.41 -0.1
3,709,321 - Rv3323c 0.41 -0.6
3,709,323 + Rv3323c 0.41 -0.2
3,709,323 + Rv3323c 0.41 -0.5
3,709,324 - Rv3323c 0.41 +1.1
3,709,357 + Rv3323c 0.46 +0.0
3,709,357 + Rv3323c 0.46 -1.1
3,709,458 + Rv3323c 0.61 -0.2
3,709,459 - Rv3323c 0.62 +1.1
3,709,487 + Rv3323c 0.66 +0.0
3,709,487 + Rv3323c 0.66 +2.1
3,709,693 - -0.9
3,709,709 - +0.5
3,709,915 + Rv3324c 0.37 -0.8
3,709,915 + Rv3324c 0.37 -0.5
3,709,915 + Rv3324c 0.37 +0.6
3,709,915 + Rv3324c 0.37 -0.0
3,709,915 + Rv3324c 0.37 +0.4
3,709,916 - Rv3324c 0.38 +0.2
3,709,916 - Rv3324c 0.38 +1.4
3,709,916 - Rv3324c 0.38 +0.2
3,710,048 - Rv3324c 0.62 -0.2
3,710,072 + Rv3324c 0.67 +0.9
3,710,072 + Rv3324c 0.67 -0.4
3,710,073 - Rv3324c 0.67 +0.8
3,710,224 + -0.5
3,710,224 + -0.5

Or see this region's nucleotide sequence