Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3092c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3091 and Rv3092c are separated by 6 nucleotidesRv3092c and Rv3093c are separated by 25 nucleotides Rv3091: Rv3091 - Conserved protein, at 3,459,116 to 3,460,807 Rv3091 Rv3092c: Rv3092c - Probable conserved integral membrane protein, at 3,460,814 to 3,461,734 Rv3092c Rv3093c: Rv3093c - Hypothetical oxidoreductase, at 3,461,760 to 3,462,764 Rv3093c Position (kb) 3460 3461 3462Strain fitness (log2 ratio) -2 -1 0 1 2 3at 3459.816 kb on - strand, within Rv3091at 3460.023 kb on - strand, within Rv3091at 3460.806 kb on - strandat 3460.964 kb on + strand, within Rv3092cat 3460.964 kb on + strand, within Rv3092cat 3460.964 kb on + strand, within Rv3092cat 3460.965 kb on - strand, within Rv3092cat 3460.965 kb on - strand, within Rv3092cat 3460.965 kb on - strand, within Rv3092cat 3461.024 kb on + strand, within Rv3092cat 3461.024 kb on + strand, within Rv3092cat 3461.196 kb on + strand, within Rv3092cat 3461.196 kb on + strand, within Rv3092cat 3461.196 kb on + strand, within Rv3092cat 3461.196 kb on + strand, within Rv3092cat 3461.197 kb on - strand, within Rv3092cat 3461.303 kb on + strand, within Rv3092cat 3461.415 kb on + strand, within Rv3092cat 3461.424 kb on + strand, within Rv3092cat 3461.424 kb on + strand, within Rv3092cat 3461.425 kb on - strand, within Rv3092cat 3461.425 kb on - strand, within Rv3092cat 3461.425 kb on - strand, within Rv3092cat 3461.425 kb on - strand, within Rv3092cat 3461.583 kb on + strand, within Rv3092cat 3461.584 kb on - strand, within Rv3092cat 3462.071 kb on - strand, within Rv3093cat 3462.362 kb on - strand, within Rv3093cat 3462.384 kb on + strand, within Rv3093cat 3462.384 kb on + strand, within Rv3093cat 3462.640 kb on + strand, within Rv3093cat 3462.640 kb on + strand, within Rv3093cat 3462.640 kb on + strand, within Rv3093cat 3462.640 kb on + strand, within Rv3093cat 3462.641 kb on - strand, within Rv3093c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL
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3,459,816 - Rv3091 0.41 -0.1
3,460,023 - Rv3091 0.54 -0.5
3,460,806 - -0.3
3,460,964 + Rv3092c 0.16 -0.2
3,460,964 + Rv3092c 0.16 -0.7
3,460,964 + Rv3092c 0.16 -0.1
3,460,965 - Rv3092c 0.16 +2.1
3,460,965 - Rv3092c 0.16 -0.4
3,460,965 - Rv3092c 0.16 -0.7
3,461,024 + Rv3092c 0.23 -1.1
3,461,024 + Rv3092c 0.23 -0.1
3,461,196 + Rv3092c 0.41 +1.0
3,461,196 + Rv3092c 0.41 +0.4
3,461,196 + Rv3092c 0.41 +0.2
3,461,196 + Rv3092c 0.41 +0.6
3,461,197 - Rv3092c 0.42 -0.8
3,461,303 + Rv3092c 0.53 +3.1
3,461,415 + Rv3092c 0.65 +0.4
3,461,424 + Rv3092c 0.66 +3.1
3,461,424 + Rv3092c 0.66 +0.1
3,461,425 - Rv3092c 0.66 -0.4
3,461,425 - Rv3092c 0.66 -1.1
3,461,425 - Rv3092c 0.66 -0.3
3,461,425 - Rv3092c 0.66 -2.5
3,461,583 + Rv3092c 0.83 -0.9
3,461,584 - Rv3092c 0.84 -0.2
3,462,071 - Rv3093c 0.31 +0.1
3,462,362 - Rv3093c 0.60 +0.2
3,462,384 + Rv3093c 0.62 -0.4
3,462,384 + Rv3093c 0.62 -0.6
3,462,640 + Rv3093c 0.88 +0.2
3,462,640 + Rv3093c 0.88 -0.7
3,462,640 + Rv3093c 0.88 -0.5
3,462,640 + Rv3093c 0.88 -1.1
3,462,641 - Rv3093c 0.88 -0.2

Or see this region's nucleotide sequence