Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2450c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
2,750,947	+		Rv2449c	0.50	-0.2
2,750,947	+		Rv2449c	0.50	-0.4
2,750,948	-		Rv2449c	0.50	+2.1
2,750,948	-		Rv2449c	0.50	+1.5
2,750,948	-		Rv2449c	0.50	+0.5
2,750,958	+		Rv2449c	0.51	-0.1
2,750,959	-		Rv2449c	0.51	-0.6
2,750,985	-		Rv2449c	0.53	-0.7
2,751,109	+		Rv2449c	0.63	+0.2
2,751,112	-		Rv2449c	0.63	-0.6
2,751,112	-		Rv2449c	0.63	-1.7
2,751,118	+		Rv2449c	0.64	+0.5
2,751,119	-		Rv2449c	0.64	-0.4
2,751,119	-		Rv2449c	0.64	-0.5
2,751,200	-		Rv2449c	0.70	+0.9
2,751,250	+		Rv2449c	0.74	+0.3
2,751,304	+		Rv2449c	0.79	-0.4
2,751,304	+		Rv2449c	0.79	+1.1
2,751,305	-		Rv2449c	0.79	+0.6
2,751,496	+				-0.7
2,751,496	+				-0.2
2,751,497	-				+2.7
2,751,563	+				+0.5
2,751,584	+				-0.8
2,751,817	-		Rv2450c	0.30	-0.8
2,751,817	-		Rv2450c	0.30	-0.4
2,751,817	-		Rv2450c	0.30	-1.3
2,751,817	-		Rv2450c	0.30	+0.1
2,751,817	-		Rv2450c	0.30	-1.0
2,751,819	+		Rv2450c	0.30	-1.5
2,751,819	+		Rv2450c	0.30	-0.0
2,751,820	-		Rv2450c	0.30	-0.6
2,751,820	-		Rv2450c	0.30	+1.7
2,751,891	+		Rv2450c	0.44	-0.9
2,751,892	-		Rv2450c	0.44	-0.9
2,751,892	-		Rv2450c	0.44	-1.2
2,752,233	+				-1.5
2,752,390	-		Rv2451	0.32	-0.3
2,752,447	+		Rv2451	0.46	-0.2
2,752,479	+		Rv2451	0.54	-0.6
2,752,483	+		Rv2451	0.55	-0.7
2,752,563	+		Rv2451	0.75	-0.5
2,752,563	+		Rv2451	0.75	+1.6
2,752,563	+		Rv2451	0.75	+2.1
2,752,564	-		Rv2451	0.76	+1.7
2,752,744	+				+0.5
2,752,760	+				-0.7
2,752,760	+				-0.9
2,752,761	-				-0.4
2,752,782	-				+0.1
2,752,805	+				-2.4
2,752,922	+		Rv2452c	0.50	-0.5
2,752,947	+		Rv2452c	0.67	-0.8
2,752,947	+		Rv2452c	0.67	-0.3
2,753,013	+				-1.1