Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2262c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
2,533,868	+		Rv2260	0.85	-0.3
2,534,011	+				+0.7
2,534,012	-				+1.0
2,534,243	-		Rv2261c	0.48	-0.4
2,534,377	-		Rv2261c	0.79	-1.0
2,534,571	-				-1.2
2,534,571	-				-0.1
2,534,603	+		Rv2262c	0.12	+1.0
2,534,603	+		Rv2262c	0.12	-0.8
2,534,648	+		Rv2262c	0.16	-0.8
2,534,649	-		Rv2262c	0.17	-1.0
2,534,649	-		Rv2262c	0.17	-0.8
2,534,875	+		Rv2262c	0.37	-2.1
2,534,927	+		Rv2262c	0.42	+0.2
2,534,928	-		Rv2262c	0.42	-0.6
2,535,025	-		Rv2262c	0.51	-0.6
2,535,082	+		Rv2262c	0.57	-1.1
2,535,330	-		Rv2262c	0.79	-0.9
2,535,604	-				-0.2
2,535,604	-				-0.7
2,535,604	-				+0.7
2,535,604	-				-0.6
2,535,763	-		Rv2263	0.13	+1.5
2,535,763	-		Rv2263	0.13	-0.2
2,535,971	-		Rv2263	0.35	+0.1
2,536,148	+		Rv2263	0.53	-0.5
2,536,149	-		Rv2263	0.53	-1.4
2,536,166	+		Rv2263	0.55	-2.4
2,536,340	+		Rv2263	0.73	-0.0
2,536,341	-		Rv2263	0.73	-1.0
2,536,409	+		Rv2263	0.81	-0.2
2,536,409	+		Rv2263	0.81	-2.4
2,536,409	+		Rv2263	0.81	-0.5
2,536,409	+		Rv2263	0.81	+0.5
2,536,410	-		Rv2263	0.81	+1.0
2,536,410	-		Rv2263	0.81	-0.6
2,536,410	-		Rv2263	0.81	-0.3
2,536,448	+		Rv2263	0.85	+1.3
2,536,466	+		Rv2263	0.86	-0.5