Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2100

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
2,357,415	-		Rv2098c	0.53	-0.9
2,357,948	+				-0.9
2,357,948	+				-0.1
2,357,949	-				+1.1
2,358,024	-				-0.1
2,358,045	+				+0.5
2,358,153	+		Rv2099c	0.69	-2.0
2,358,154	-		Rv2099c	0.70	-1.4
2,358,261	+				+0.2
2,358,262	-				-1.2
2,358,272	+				-1.1
2,358,272	+				+1.0
2,358,272	+				-0.5
2,358,273	-				+1.6
2,358,273	-				-0.1
2,358,278	-				-1.2
2,358,490	+				-0.3
2,358,728	-		Rv2100	0.21	-0.6
2,358,857	+		Rv2100	0.28	+0.6
2,359,010	-		Rv2100	0.38	+2.7
2,359,010	-		Rv2100	0.38	-0.5
2,359,032	+		Rv2100	0.39	-0.1
2,359,032	+		Rv2100	0.39	+0.1
2,359,032	+		Rv2100	0.39	-0.0
2,359,032	+		Rv2100	0.39	+0.6
2,359,033	-		Rv2100	0.39	-0.5
2,359,033	-		Rv2100	0.39	-0.4
2,359,033	-		Rv2100	0.39	+1.1
2,359,088	+		Rv2100	0.42	+0.0
2,359,089	-		Rv2100	0.42	-0.2
2,359,089	-		Rv2100	0.42	+2.1
2,359,089	-		Rv2100	0.42	-0.4
2,359,089	-		Rv2100	0.42	-0.4
2,359,776	+		Rv2100	0.84	+0.2
2,359,820	+		Rv2100	0.87	+0.1
2,359,820	+		Rv2100	0.87	-0.9
2,359,820	+		Rv2100	0.87	+0.7
2,359,820	+		Rv2100	0.87	-0.5
2,359,821	-		Rv2100	0.87	-1.1
2,359,821	-		Rv2100	0.87	+1.5
2,359,821	-		Rv2100	0.87	-1.0
2,359,821	-		Rv2100	0.87	-0.6
2,359,825	+		Rv2100	0.87	-0.4
2,359,882	-				+1.1
2,360,006	+				-0.4
2,360,006	+				-0.6
2,360,006	+				+2.1
2,360,006	+				-0.4
2,360,006	+				-0.0
2,360,007	-				-0.3
2,360,132	+				+0.3
2,360,133	-				-0.7
2,360,388	+				-0.7
2,360,388	+				+0.1
2,360,610	-		Rv2101	0.12	-1.0