Experiment: 7H9 with Ethionamide 0.1 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1941 and Rv1942c are separated by 209 nucleotides Rv1942c and Rv1943c overlap by 4 nucleotides Rv1943c and Rv1944c overlap by 4 nucleotides Rv1944c and Rv1945 are separated by 54 nucleotides
Rv1941: Rv1941 - Probable short-chain type dehydrogenase/reductase, at 2,193,664 to 2,194,434
Rv1941
Rv1942c: Rv1942c - Possible toxin MazF5, at 2,194,644 to 2,194,973
Rv1942c
Rv1943c: Rv1943c - Possible antitoxin MazE5, at 2,194,970 to 2,195,347
Rv1943c
Rv1944c: Rv1944c - Conserved protein, at 2,195,344 to 2,195,934
Rv1944c
Rv1945: Rv1945 - Conserved hypothetical protein, at 2,195,989 to 2,197,353
Rv1945
Position (kb)
2195
2196 Strain fitness (log2 ratio)
-1
0
1
2 at 2194.493 kb on + strand at 2195.004 kb on - strand at 2195.055 kb on + strand, within Rv1943c at 2195.056 kb on - strand, within Rv1943c at 2195.056 kb on - strand, within Rv1943c at 2195.490 kb on - strand, within Rv1944c at 2195.636 kb on + strand, within Rv1944c at 2195.868 kb on - strand, within Rv1944c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL remove 2,194,493 + -0.8 2,195,004 - -0.6 2,195,055 + Rv1943c 0.22 +2.1 2,195,056 - Rv1943c 0.23 +0.0 2,195,056 - Rv1943c 0.23 -0.6 2,195,490 - Rv1944c 0.25 -1.2 2,195,636 + Rv1944c 0.49 -0.8 2,195,868 - Rv1944c 0.89 -0.9
Or see this region's nucleotide sequence