Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1661

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
1,874,334	+		Rv1660	0.16	-0.5
1,874,335	-		Rv1660	0.16	-0.6
1,874,611	-		Rv1660	0.42	+0.4
1,874,674	-		Rv1660	0.48	-0.2
1,874,820	+		Rv1660	0.62	-0.5
1,874,821	-		Rv1660	0.62	-0.1
1,874,913	+		Rv1660	0.71	-1.4
1,874,914	-		Rv1660	0.71	-0.4
1,874,914	-		Rv1660	0.71	+0.5
1,875,240	+				-0.4
1,875,581	-				+0.2
1,875,874	+				-0.0
1,875,875	-				+0.1
1,875,875	-				-0.3
1,875,875	-				-2.1
1,876,082	-		Rv1661	0.12	-0.4
1,876,293	-		Rv1661	0.15	-0.8
1,877,043	-		Rv1661	0.27	-0.5
1,877,043	-		Rv1661	0.27	-0.6
1,877,288	-		Rv1661	0.31	-2.1
1,878,017	-		Rv1661	0.43	-0.8
1,879,343	+		Rv1661	0.63	-1.3
1,879,345	+		Rv1661	0.63	-0.5
1,879,346	-		Rv1661	0.63	+1.5
1,879,556	-		Rv1661	0.67	-1.0
1,880,070	-		Rv1661	0.75	+4.1
1,880,092	-		Rv1661	0.75	-0.4
1,880,628	+		Rv1661	0.83	+0.3
1,880,993	+		Rv1661	0.89	+2.4
1,882,045	+				-0.6