Experiment: 7H9 with Ethionamide 0.1 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1483 and Rv1484 are separated by 18 nucleotides Rv1484 and Rv1485 are separated by 5 nucleotides Rv1485 and Rv1486c overlap by 35 nucleotides Rv1486c and Rv1487 are separated by 57 nucleotides
Rv1483: Rv1483 - 3-oxoacyl-[acyl-carrier protein] reductase FabG1 (3-ketoacyl-acyl carrier protein reductase) (mycolic acid biosynthesis a protein), at 1,673,440 to 1,674,183
Rv1483
Rv1484: Rv1484 - NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase), at 1,674,202 to 1,675,011
Rv1484
Rv1485: Rv1485 - Ferrochelatase HemZ (protoheme ferro-lyase) (heme synthetase), at 1,675,017 to 1,676,051
Rv1485
Rv1486c: Rv1486c - Conserved hypothetical protein, at 1,676,017 to 1,676,883
Rv1486c
Rv1487: Rv1487 - Conserved membrane protein, at 1,676,941 to 1,677,375
Rv1487
Position (kb)
1675
1676
1677 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 1676.304 kb on + strand, within Rv1486c at 1676.304 kb on + strand, within Rv1486c at 1676.305 kb on - strand, within Rv1486c at 1676.305 kb on - strand, within Rv1486c at 1676.387 kb on + strand, within Rv1486c at 1676.387 kb on + strand, within Rv1486c at 1676.388 kb on - strand, within Rv1486c at 1676.420 kb on + strand, within Rv1486c at 1676.421 kb on - strand, within Rv1486c at 1676.421 kb on - strand, within Rv1486c at 1676.762 kb on + strand, within Rv1486c at 1676.896 kb on + strand at 1676.896 kb on + strand at 1676.930 kb on - strand at 1676.935 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL remove 1,676,304 + Rv1486c 0.33 -0.3 1,676,304 + Rv1486c 0.33 -2.5 1,676,305 - Rv1486c 0.33 -0.5 1,676,305 - Rv1486c 0.33 -1.3 1,676,387 + Rv1486c 0.43 +0.9 1,676,387 + Rv1486c 0.43 -2.2 1,676,388 - Rv1486c 0.43 -0.2 1,676,420 + Rv1486c 0.46 +0.4 1,676,421 - Rv1486c 0.47 -1.0 1,676,421 - Rv1486c 0.47 +2.1 1,676,762 + Rv1486c 0.86 -0.7 1,676,896 + -0.0 1,676,896 + +0.2 1,676,930 - -0.7 1,676,935 - -1.4
Or see this region's nucleotide sequence