Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1290A

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
1,444,064	+		Rv1290c	0.37	-1.1
1,444,064	+		Rv1290c	0.37	+3.4
1,444,065	-		Rv1290c	0.37	-1.6
1,444,065	-		Rv1290c	0.37	-0.1
1,444,153	-		Rv1290c	0.43	+0.4
1,444,153	-		Rv1290c	0.43	+0.1
1,444,153	-		Rv1290c	0.43	-0.6
1,444,169	-		Rv1290c	0.44	-0.5
1,444,184	-		Rv1290c	0.45	+0.1
1,444,235	+		Rv1290c	0.48	-2.2
1,444,235	+		Rv1290c	0.48	-1.0
1,444,239	+		Rv1290c	0.48	-0.7
1,444,298	+		Rv1290c	0.52	-0.7
1,444,299	-		Rv1290c	0.52	+0.7
1,444,299	-		Rv1290c	0.52	-2.3
1,444,330	-		Rv1290c	0.54	-0.4
1,444,385	+		Rv1290c	0.58	+0.1
1,444,385	+		Rv1290c	0.58	+0.2
1,444,385	+		Rv1290c	0.58	+2.1
1,444,386	-		Rv1290c	0.58	+0.2
1,444,419	+		Rv1290c	0.60	+0.4
1,444,420	-		Rv1290c	0.60	+0.4
1,444,520	+		Rv1290c	0.66	+2.1
1,444,520	+		Rv1290c	0.66	-0.6
1,444,520	+		Rv1290c	0.66	+0.2
1,444,601	+		Rv1290c	0.71	+0.4
1,444,601	+		Rv1290c	0.71	-1.1
1,444,601	+		Rv1290c	0.71	-0.3
1,444,850	+		Rv1290c	0.87	-0.6
1,444,851	-		Rv1290c	0.87	-0.4
1,444,851	-		Rv1290c	0.87	+0.1
1,444,855	-		Rv1290c	0.88	+2.4
1,444,906	-				-0.3
1,444,940	+				-0.4
1,444,940	+				+0.2
1,444,940	+				-0.5
1,444,940	+				-1.0
1,444,941	-				-0.8
1,444,944	+				-2.0
1,444,945	-				-0.1
1,444,963	+				+1.0
1,445,187	-		Rv1290A	0.41	+1.1
1,445,391	+				-0.6
1,445,428	+				-0.1
1,445,429	-				+2.1
1,445,429	-				-0.4
1,445,501	-				-1.2
1,445,527	+				-1.5
1,445,780	+		Rv1291c	0.84	-0.6
1,445,922	-				-0.8
1,445,935	+				-0.8
1,446,086	-				-1.2
1,446,123	+				+0.4
1,446,124	-				+1.1
1,446,180	-				-0.1
1,446,304	-				-1.3