Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1140

Experiment: 7H9 with Ethionamide 0.1 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethionamide 0.1 ug/mL
1,266,488	+				+0.9
1,266,624	+		Rv1139c	0.28	-1.0
1,266,625	-		Rv1139c	0.28	-0.4
1,266,788	+		Rv1139c	0.60	-1.6
1,266,867	+		Rv1139c	0.76	+1.0
1,266,867	+		Rv1139c	0.76	-0.6
1,266,868	-		Rv1139c	0.76	-4.2
1,266,978	+				-1.1
1,266,979	-				-2.0
1,266,979	-				+1.4
1,266,979	-				-0.6
1,266,982	-				-0.5
1,266,982	-				+0.6
1,266,982	-				-2.2
1,266,991	+				-1.7
1,266,991	+				-0.4
1,267,032	+				-0.3
1,267,085	+				+0.2
1,267,086	-				-0.5
1,267,086	-				-0.4
1,267,110	-				-0.1
1,267,319	-				-1.1
1,267,804	+		Rv1140	0.54	-0.1
1,267,805	-		Rv1140	0.54	+0.8
1,268,542	+		Rv1141c	0.42	-1.0
1,268,576	-		Rv1141c	0.46	-0.0
1,268,608	-		Rv1141c	0.50	-0.9
1,268,620	+		Rv1141c	0.52	-2.0
1,268,716	+		Rv1141c	0.64	-0.1
1,268,784	+		Rv1141c	0.72	-0.6
1,268,784	+		Rv1141c	0.72	-0.5
1,268,785	-		Rv1141c	0.72	-0.1
1,268,785	-		Rv1141c	0.72	-0.6
1,268,984	-				-0.1
1,269,022	-				-0.6
1,269,022	-				-0.2
1,269,022	-				+0.9
1,269,050	-				+0.3
1,269,099	+				-0.4
1,269,100	-				-1.6