Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1126c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1125 and Rv1126c are separated by 3 nucleotidesRv1126c and Rv1127c overlap by 4 nucleotides Rv1125: Rv1125 - Conserved hypothetical protein, at 1,248,082 to 1,249,326 Rv1125 Rv1126c: Rv1126c - Conserved protein, at 1,249,330 to 1,249,935 Rv1126c Rv1127c: Rv1127c - Probable pyruvate, phosphate dikinase PpdK, at 1,249,932 to 1,251,404 Rv1127c Position (kb) 1249 1250Strain fitness (log2 ratio) -1 0 1at 1248.397 kb on - strand, within Rv1125at 1248.645 kb on + strand, within Rv1125at 1250.902 kb on + strand, within Rv1127c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL
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1,248,397 - Rv1125 0.25 -0.3
1,248,645 + Rv1125 0.45 +0.0
1,250,902 + Rv1127c 0.66 -1.6

Or see this region's nucleotide sequence