Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0816c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0815c and Rv0816c are separated by 292 nucleotidesRv0816c and Rv0817c overlap by 4 nucleotidesRv0817c and Rv0818 are separated by 129 nucleotides Rv0815c: Rv0815c - Probable thiosulfate sulfurtransferase CysA2 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotransferase), at 908,485 to 909,318 Rv0815c Rv0816c: Rv0816c - Probable thioredoxin ThiX, at 909,611 to 910,033 Rv0816c Rv0817c: Rv0817c - Probable conserved exported protein, at 910,030 to 910,842 Rv0817c Rv0818: Rv0818 - Transcriptional regulatory protein, at 910,972 to 911,739 Rv0818 Position (kb) 909 910 911Strain fitness (log2 ratio) -2 -1 0 1 2 3at 909.337 kb on + strandat 909.337 kb on + strandat 909.385 kb on + strandat 909.385 kb on + strandat 909.386 kb on - strandat 909.386 kb on - strandat 909.440 kb on + strandat 909.454 kb on + strandat 909.455 kb on - strandat 909.464 kb on + strandat 909.464 kb on + strandat 909.464 kb on + strandat 909.500 kb on + strandat 909.501 kb on - strandat 909.605 kb on + strandat 909.605 kb on + strandat 909.825 kb on - strand, within Rv0816cat 910.003 kb on + strandat 910.003 kb on + strandat 910.004 kb on - strandat 910.004 kb on - strandat 910.895 kb on + strandat 910.901 kb on + strandat 910.982 kb on + strandat 910.982 kb on + strandat 910.982 kb on + strandat 910.982 kb on + strandat 910.983 kb on - strandat 910.983 kb on - strandat 910.983 kb on - strandat 910.985 kb on + strandat 910.985 kb on + strandat 910.985 kb on + strandat 910.985 kb on + strandat 910.985 kb on + strandat 910.985 kb on + strandat 910.986 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL
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909,337 + +1.4
909,337 + +0.2
909,385 + -2.2
909,385 + -2.0
909,386 - +0.3
909,386 - +0.2
909,440 + -0.5
909,454 + +0.5
909,455 - -0.4
909,464 + +0.3
909,464 + -0.6
909,464 + -0.5
909,500 + +2.1
909,501 - +1.8
909,605 + +1.6
909,605 + -0.8
909,825 - Rv0816c 0.51 -0.0
910,003 + -0.4
910,003 + -0.2
910,004 - -0.6
910,004 - +0.5
910,895 + -0.2
910,901 + +2.1
910,982 + +0.4
910,982 + +1.7
910,982 + -0.4
910,982 + -0.6
910,983 - +1.4
910,983 - +2.1
910,983 - +0.7
910,985 + -0.0
910,985 + +3.7
910,985 + +0.4
910,985 + +1.1
910,985 + +1.5
910,985 + -1.6
910,986 - +1.9

Or see this region's nucleotide sequence