Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0575c

Experiment: 7H9 with Ethionamide 0.1 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0574c and Rv0575c are separated by 184 nucleotidesRv0575c and Rv0576 are separated by 102 nucleotides Rv0574c: Rv0574c - Conserved hypothetical protein, at 667,252 to 668,394 Rv0574c Rv0575c: Rv0575c - Possible oxidoreductase, at 668,579 to 669,745 Rv0575c Rv0576: Rv0576 - Probable transcriptional regulatory protein (possibly ArsR-family), at 669,848 to 671,152 Rv0576 Position (kb) 668 669 670Strain fitness (log2 ratio) -2 -1 0 1 2 3at 667.676 kb on + strand, within Rv0574cat 667.677 kb on - strand, within Rv0574cat 667.709 kb on - strand, within Rv0574cat 668.087 kb on + strand, within Rv0574cat 668.261 kb on + strand, within Rv0574cat 668.280 kb on + strandat 668.282 kb on + strandat 668.282 kb on + strandat 668.282 kb on + strandat 668.283 kb on - strandat 668.440 kb on - strandat 668.446 kb on + strandat 668.447 kb on - strandat 668.447 kb on - strandat 668.447 kb on - strandat 668.461 kb on - strandat 668.548 kb on + strandat 668.549 kb on - strandat 668.835 kb on + strand, within Rv0575cat 668.835 kb on + strand, within Rv0575cat 668.881 kb on - strand, within Rv0575cat 669.154 kb on - strand, within Rv0575cat 669.154 kb on - strand, within Rv0575cat 669.162 kb on + strand, within Rv0575cat 669.162 kb on + strand, within Rv0575cat 669.162 kb on + strand, within Rv0575cat 669.162 kb on + strand, within Rv0575cat 669.226 kb on - strand, within Rv0575cat 669.417 kb on + strand, within Rv0575cat 669.418 kb on - strand, within Rv0575cat 669.549 kb on + strand, within Rv0575cat 669.550 kb on - strand, within Rv0575cat 669.627 kb on + strand, within Rv0575cat 669.627 kb on + strand, within Rv0575cat 669.628 kb on - strand, within Rv0575cat 669.888 kb on + strandat 669.889 kb on - strandat 669.919 kb on + strandat 670.029 kb on - strand, within Rv0576at 670.031 kb on + strand, within Rv0576at 670.259 kb on - strand, within Rv0576at 670.309 kb on + strand, within Rv0576at 670.310 kb on - strand, within Rv0576

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL
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667,676 + Rv0574c 0.37 +0.6
667,677 - Rv0574c 0.37 -0.6
667,709 - Rv0574c 0.40 -0.0
668,087 + Rv0574c 0.73 -0.3
668,261 + Rv0574c 0.88 +0.5
668,280 + -1.3
668,282 + -0.8
668,282 + +0.6
668,282 + +3.6
668,283 - -1.1
668,440 - -0.5
668,446 + -1.0
668,447 - +0.5
668,447 - -0.6
668,447 - -0.4
668,461 - -0.2
668,548 + +1.2
668,549 - -0.0
668,835 + Rv0575c 0.22 +1.2
668,835 + Rv0575c 0.22 +0.2
668,881 - Rv0575c 0.26 +0.5
669,154 - Rv0575c 0.49 -1.8
669,154 - Rv0575c 0.49 -0.8
669,162 + Rv0575c 0.50 +1.0
669,162 + Rv0575c 0.50 -0.3
669,162 + Rv0575c 0.50 -0.3
669,162 + Rv0575c 0.50 -1.8
669,226 - Rv0575c 0.55 +1.2
669,417 + Rv0575c 0.72 -0.0
669,418 - Rv0575c 0.72 +1.2
669,549 + Rv0575c 0.83 +0.8
669,550 - Rv0575c 0.83 -0.4
669,627 + Rv0575c 0.90 -1.0
669,627 + Rv0575c 0.90 +0.4
669,628 - Rv0575c 0.90 -0.7
669,888 + -0.3
669,889 - -1.0
669,919 + -0.3
670,029 - Rv0576 0.14 -0.2
670,031 + Rv0576 0.14 -0.4
670,259 - Rv0576 0.31 +0.0
670,309 + Rv0576 0.35 -0.7
670,310 - Rv0576 0.35 +0.2

Or see this region's nucleotide sequence