Experiment: 7H9 with Ethionamide 0.1 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0279c and Rv0280 are separated by 290 nucleotides Rv0280 and Rv0281 are separated by 23 nucleotides
Rv0279c: Rv0279c - PE-PGRS family protein PE_PGRS4, at 336,560 to 339,073
Rv0279c
Rv0280: Rv0280 - PPE family protein PPE3, at 339,364 to 340,974
Rv0280
Rv0281: Rv0281 - Possible S-adenosylmethionine-dependent methyltransferase, at 340,998 to 341,906
Rv0281
Position (kb) 339
340
341 Strain fitness (log2 ratio) -2
-1
0
1
2 at 338.889 kb on + strand at 339.154 kb on + strand at 339.182 kb on - strand at 339.504 kb on - strand at 339.559 kb on + strand, within Rv0280 at 339.559 kb on + strand, within Rv0280 at 339.560 kb on - strand, within Rv0280 at 339.560 kb on - strand, within Rv0280 at 339.560 kb on - strand, within Rv0280 at 339.594 kb on - strand, within Rv0280 at 339.784 kb on + strand, within Rv0280 at 339.826 kb on + strand, within Rv0280 at 339.826 kb on + strand, within Rv0280 at 339.827 kb on - strand, within Rv0280 at 339.962 kb on - strand, within Rv0280 at 339.962 kb on - strand, within Rv0280 at 339.977 kb on + strand, within Rv0280 at 340.054 kb on + strand, within Rv0280 at 340.056 kb on + strand, within Rv0280 at 340.182 kb on - strand, within Rv0280 at 340.182 kb on - strand, within Rv0280 at 340.182 kb on - strand, within Rv0280 at 340.192 kb on + strand, within Rv0280 at 340.339 kb on - strand, within Rv0280 at 340.350 kb on - strand, within Rv0280 at 340.525 kb on + strand, within Rv0280 at 340.526 kb on - strand, within Rv0280 at 340.531 kb on + strand, within Rv0280 at 340.646 kb on + strand, within Rv0280 at 340.646 kb on + strand, within Rv0280 at 340.647 kb on - strand, within Rv0280 at 340.697 kb on - strand, within Rv0280 at 340.710 kb on + strand, within Rv0280 at 340.710 kb on + strand, within Rv0280 at 340.710 kb on + strand, within Rv0280 at 340.710 kb on + strand, within Rv0280 at 340.716 kb on + strand, within Rv0280 at 340.717 kb on - strand, within Rv0280 at 341.015 kb on + strand at 341.116 kb on - strand, within Rv0281 at 341.247 kb on + strand, within Rv0281 at 341.248 kb on - strand, within Rv0281 at 341.248 kb on - strand, within Rv0281 at 341.260 kb on - strand, within Rv0281 at 341.260 kb on - strand, within Rv0281 at 341.550 kb on + strand, within Rv0281 at 341.666 kb on + strand, within Rv0281 at 341.734 kb on - strand, within Rv0281 at 341.812 kb on - strand, within Rv0281 at 341.968 kb on + strand at 341.969 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL remove 338,889 + +2.6 339,154 + -0.8 339,182 - +1.4 339,504 - +0.5 339,559 + Rv0280 0.12 +1.1 339,559 + Rv0280 0.12 +0.3 339,560 - Rv0280 0.12 -0.0 339,560 - Rv0280 0.12 -1.8 339,560 - Rv0280 0.12 +1.0 339,594 - Rv0280 0.14 +1.1 339,784 + Rv0280 0.26 +1.1 339,826 + Rv0280 0.29 +0.0 339,826 + Rv0280 0.29 -0.6 339,827 - Rv0280 0.29 -1.0 339,962 - Rv0280 0.37 +1.4 339,962 - Rv0280 0.37 +0.2 339,977 + Rv0280 0.38 +0.9 340,054 + Rv0280 0.43 +0.5 340,056 + Rv0280 0.43 +2.1 340,182 - Rv0280 0.51 +1.8 340,182 - Rv0280 0.51 +0.1 340,182 - Rv0280 0.51 +0.8 340,192 + Rv0280 0.51 +0.7 340,339 - Rv0280 0.61 +0.6 340,350 - Rv0280 0.61 +0.5 340,525 + Rv0280 0.72 +0.4 340,526 - Rv0280 0.72 -0.0 340,531 + Rv0280 0.72 +0.6 340,646 + Rv0280 0.80 -0.5 340,646 + Rv0280 0.80 +2.1 340,647 - Rv0280 0.80 -0.7 340,697 - Rv0280 0.83 +0.2 340,710 + Rv0280 0.84 +0.8 340,710 + Rv0280 0.84 +2.3 340,710 + Rv0280 0.84 -0.8 340,710 + Rv0280 0.84 +0.3 340,716 + Rv0280 0.84 +0.8 340,717 - Rv0280 0.84 -0.0 341,015 + +1.4 341,116 - Rv0281 0.13 +0.1 341,247 + Rv0281 0.27 +0.1 341,248 - Rv0281 0.28 +2.1 341,248 - Rv0281 0.28 -1.0 341,260 - Rv0281 0.29 +1.1 341,260 - Rv0281 0.29 -0.9 341,550 + Rv0281 0.61 -0.2 341,666 + Rv0281 0.73 +1.1 341,734 - Rv0281 0.81 -0.6 341,812 - Rv0281 0.90 +0.3 341,968 + -0.5 341,969 - -1.4
Or see this region's nucleotide sequence