Experiment: 7H9 with Ethionamide 0.1 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0195 and Rv0196 are separated by 112 nucleotides Rv0196 and Rv0197 overlap by 1 nucleotides Rv0197 and Rv0198c overlap by 4 nucleotides
Rv0195: Rv0195 - Possible two component transcriptional regulatory protein (probably LuxR-family), at 230,899 to 231,534
Rv0195
Rv0196: Rv0196 - Possible transcriptional regulatory protein, at 231,647 to 232,231
Rv0196
Rv0197: Rv0197 - Possible oxidoreductase, at 232,231 to 234,519
Rv0197
Rv0198c: Rv0198c - Probable zinc metalloprotease Zmp1, at 234,516 to 236,507
Rv0198c
Position (kb) 232
233
234
235 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 231.383 kb on + strand, within Rv0195 at 231.427 kb on + strand, within Rv0195 at 231.428 kb on - strand, within Rv0195 at 231.464 kb on + strand, within Rv0195 at 231.464 kb on + strand, within Rv0195 at 231.464 kb on + strand, within Rv0195 at 231.464 kb on + strand, within Rv0195 at 231.464 kb on + strand, within Rv0195 at 231.464 kb on + strand, within Rv0195 at 231.555 kb on + strand at 231.555 kb on + strand at 231.555 kb on + strand at 231.555 kb on + strand at 231.556 kb on - strand at 231.556 kb on - strand at 231.589 kb on + strand at 231.589 kb on + strand at 231.626 kb on + strand at 231.626 kb on + strand at 231.626 kb on + strand at 231.627 kb on - strand at 231.767 kb on + strand, within Rv0196 at 231.768 kb on - strand, within Rv0196 at 231.768 kb on - strand, within Rv0196 at 231.774 kb on - strand, within Rv0196 at 231.896 kb on + strand, within Rv0196 at 232.071 kb on + strand, within Rv0196 at 232.071 kb on + strand, within Rv0196 at 232.072 kb on - strand, within Rv0196 at 232.360 kb on + strand at 232.393 kb on + strand at 232.541 kb on - strand, within Rv0197 at 232.541 kb on - strand, within Rv0197 at 232.543 kb on + strand, within Rv0197 at 232.543 kb on + strand, within Rv0197 at 232.543 kb on + strand, within Rv0197 at 233.357 kb on + strand, within Rv0197 at 233.643 kb on - strand, within Rv0197 at 233.701 kb on + strand, within Rv0197 at 233.762 kb on - strand, within Rv0197 at 233.770 kb on + strand, within Rv0197 at 234.110 kb on - strand, within Rv0197 at 234.326 kb on - strand at 234.589 kb on + strand at 234.590 kb on - strand at 234.991 kb on + strand, within Rv0198c at 235.145 kb on - strand, within Rv0198c at 235.145 kb on - strand, within Rv0198c at 235.212 kb on + strand, within Rv0198c at 235.213 kb on - strand, within Rv0198c at 235.259 kb on - strand, within Rv0198c at 235.473 kb on + strand, within Rv0198c at 235.473 kb on + strand, within Rv0198c at 235.477 kb on + strand, within Rv0198c at 235.477 kb on + strand, within Rv0198c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ethionamide 0.1 ug/mL remove 231,383 + Rv0195 0.76 -0.1 231,427 + Rv0195 0.83 -0.2 231,428 - Rv0195 0.83 -1.6 231,464 + Rv0195 0.89 -0.4 231,464 + Rv0195 0.89 -0.3 231,464 + Rv0195 0.89 -0.6 231,464 + Rv0195 0.89 -0.2 231,464 + Rv0195 0.89 -1.7 231,464 + Rv0195 0.89 -0.4 231,555 + -0.0 231,555 + -0.0 231,555 + -0.4 231,555 + -1.1 231,556 - -0.1 231,556 - -0.6 231,589 + -1.0 231,589 + +0.9 231,626 + +0.1 231,626 + -0.0 231,626 + -1.6 231,627 - -0.4 231,767 + Rv0196 0.21 -0.1 231,768 - Rv0196 0.21 +2.1 231,768 - Rv0196 0.21 -3.0 231,774 - Rv0196 0.22 -0.6 231,896 + Rv0196 0.43 +0.6 232,071 + Rv0196 0.72 -1.1 232,071 + Rv0196 0.72 +0.6 232,072 - Rv0196 0.73 -0.1 232,360 + -0.7 232,393 + -0.6 232,541 - Rv0197 0.14 -0.4 232,541 - Rv0197 0.14 -0.3 232,543 + Rv0197 0.14 +0.5 232,543 + Rv0197 0.14 -0.3 232,543 + Rv0197 0.14 -1.0 233,357 + Rv0197 0.49 -0.4 233,643 - Rv0197 0.62 -0.5 233,701 + Rv0197 0.64 +1.0 233,762 - Rv0197 0.67 -1.2 233,770 + Rv0197 0.67 -3.1 234,110 - Rv0197 0.82 -2.1 234,326 - -0.0 234,589 + -0.2 234,590 - -0.7 234,991 + Rv0198c 0.24 -1.2 235,145 - Rv0198c 0.32 +1.1 235,145 - Rv0198c 0.32 -0.3 235,212 + Rv0198c 0.35 -2.6 235,213 - Rv0198c 0.35 -0.8 235,259 - Rv0198c 0.37 -0.2 235,473 + Rv0198c 0.48 +0.1 235,473 + Rv0198c 0.48 +0.6 235,477 + Rv0198c 0.48 +0.0 235,477 + Rv0198c 0.48 -0.0
Or see this region's nucleotide sequence