Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3892c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
4,373,551	-				-0.8
4,373,595	+				-1.0
4,373,595	+				+0.8
4,373,595	+				-0.7
4,373,596	-				-0.6
4,373,599	-				-1.4
4,373,652	+				+1.7
4,373,652	+				+2.4
4,373,652	+				+3.3
4,373,695	+				+0.2
4,373,727	+				+1.4
4,373,728	-				+0.1
4,373,788	+		Rv3890c	0.22	+0.2
4,373,789	-		Rv3890c	0.22	-0.6
4,373,789	-		Rv3890c	0.22	-0.5
4,373,925	+		Rv3890c	0.69	-0.2
4,373,925	+		Rv3890c	0.69	-1.4
4,373,926	-		Rv3890c	0.69	+0.6
4,373,969	+		Rv3890c	0.84	-0.4
4,373,993	-				+1.0
4,373,994	+				-0.4
4,373,994	+				-0.6
4,373,994	+				-0.0
4,373,995	-				-0.5
4,373,995	-				-1.8
4,374,208	-		Rv3891c	0.49	+1.4
4,374,208	-		Rv3891c	0.49	-0.0
4,374,272	-		Rv3891c	0.69	-0.7
4,374,272	-		Rv3891c	0.69	+0.4
4,374,276	-		Rv3891c	0.70	-0.4
4,374,414	+				+2.4
4,374,436	+				-0.0
4,374,436	+				-0.2
4,374,437	-				-0.2
4,374,437	-				-0.3
4,374,437	-				+0.5
4,374,437	-				+1.8
4,374,479	+				-0.8
4,375,208	+		Rv3892c	0.60	+0.1
4,375,208	+		Rv3892c	0.60	-0.4
4,375,208	+		Rv3892c	0.60	+0.6
4,375,208	+		Rv3892c	0.60	-0.6
4,375,208	+		Rv3892c	0.60	-0.4
4,375,208	+		Rv3892c	0.60	-0.0
4,375,209	-		Rv3892c	0.60	-0.2
4,375,209	-		Rv3892c	0.60	-0.8
4,375,209	-		Rv3892c	0.60	-0.6
4,375,209	-		Rv3892c	0.60	-0.2
4,375,209	-		Rv3892c	0.60	-1.5
4,375,253	+		Rv3892c	0.64	+0.1
4,375,286	-		Rv3892c	0.67	-1.0
4,375,477	-		Rv3892c	0.83	+0.2
4,375,687	+				-0.5
4,375,687	+				-0.2
4,375,687	+				-1.5
4,375,687	+				-0.4
4,375,688	-				-1.3
4,375,688	-				-0.3
4,375,688	-				+0.1
4,375,688	-				+2.4
4,375,688	-				-0.5
4,375,688	-				-1.0
4,375,691	+				-1.8
4,375,739	+				+0.6
4,375,763	+				+2.4
4,375,764	-				-2.3
4,375,764	-				-0.4
4,375,814	+		Rv3893c	0.22	+0.0
4,375,815	-		Rv3893c	0.23	-0.2
4,375,887	+		Rv3893c	0.53	+0.2
4,375,888	-		Rv3893c	0.54	+1.4
4,376,042	+				+4.7
4,376,042	+				-1.5
4,376,043	-				-1.3
4,376,184	-				-0.6
4,376,232	+				-1.0
4,376,246	-				-0.2
4,376,402	+				-0.3
4,376,403	-				+0.7
4,376,404	+				-0.4
4,376,405	-				-0.8
4,376,405	-				-1.4
4,376,405	-				-0.7
4,376,405	-				+3.4
4,376,493	+				+1.7
4,376,494	-				-2.9