Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3844

Experiment: 7H9 with Isoniazid 0.025 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3844 and Rv3845 are separated by 14 nucleotides Rv3844: Rv3844 - Possible transposase, at 4,318,775 to 4,319,266 Rv3844 Rv3845: Rv3845 - Hypothetical protein, at 4,319,281 to 4,319,640 Rv3845 Position (kb) 4318 4319 4320Strain fitness (log2 ratio) -1 0 1 2 3 4 5 6at 4317.946 kb on - strandat 4318.248 kb on + strandat 4318.332 kb on + strandat 4318.333 kb on - strandat 4318.348 kb on - strandat 4318.348 kb on - strandat 4318.348 kb on - strandat 4319.564 kb on - strand, within Rv3845at 4319.931 kb on - strandat 4320.093 kb on + strandat 4320.150 kb on + strandat 4320.154 kb on + strandat 4320.154 kb on + strandat 4320.155 kb on - strandat 4320.155 kb on - strandat 4320.155 kb on - strandat 4320.166 kb on + strandat 4320.167 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL
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4,317,946 - +1.4
4,318,248 + -1.6
4,318,332 + -0.1
4,318,333 - +0.8
4,318,348 - +0.8
4,318,348 - -0.4
4,318,348 - +0.4
4,319,564 - Rv3845 0.79 +2.4
4,319,931 - -0.8
4,320,093 + -0.4
4,320,150 + +0.2
4,320,154 + -0.1
4,320,154 + -0.6
4,320,155 - +0.5
4,320,155 - +6.6
4,320,155 - -0.9
4,320,166 + -0.4
4,320,167 - -0.9

Or see this region's nucleotide sequence