Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3769

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
4,213,623	+		Rv3767c	0.66	+0.1
4,213,661	-		Rv3767c	0.70	+0.3
4,213,771	+		Rv3767c	0.82	-0.3
4,213,771	+		Rv3767c	0.82	-0.5
4,213,772	-		Rv3767c	0.82	+0.2
4,213,772	-		Rv3767c	0.82	+1.1
4,213,782	+		Rv3767c	0.83	+1.4
4,213,907	+				-0.6
4,213,982	+				+1.1
4,214,049	+				-0.7
4,214,091	-				-0.7
4,214,091	-				+2.0
4,214,254	+		Rv3768	0.51	+1.0
4,214,254	+		Rv3768	0.51	+3.0
4,214,276	-		Rv3768	0.57	-0.7
4,214,302	+		Rv3768	0.64	+2.9
4,214,472	+				+0.2
4,214,473	-				+0.3
4,214,555	+				+0.8
4,214,556	-				-0.0
4,215,064	+				-0.2
4,215,201	+				+0.8
4,215,202	-				-0.8
4,215,339	+		Rv3770c	0.24	+0.1
4,215,710	+		Rv3770c	0.89	+1.4
4,215,714	+		Rv3770c	0.89	-0.0
4,215,714	+		Rv3770c	0.89	-0.3
4,215,714	+		Rv3770c	0.89	+0.4
4,215,714	+		Rv3770c	0.89	-0.4
4,215,714	+		Rv3770c	0.89	-0.7
4,215,714	+		Rv3770c	0.89	-0.3
4,215,715	-		Rv3770c	0.89	+0.6
4,215,715	-		Rv3770c	0.89	-0.9
4,215,718	-				+0.4
4,215,746	-				-0.3
4,215,762	-				+0.2
4,215,762	-				-0.5
4,215,770	-				+0.1
4,215,778	+				+0.6
4,215,779	-				+2.4