Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3340

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
3,725,144	+		Rv3339c	0.43	-2.4
3,725,213	+		Rv3339c	0.49	-1.2
3,725,213	+		Rv3339c	0.49	+0.9
3,725,213	+		Rv3339c	0.49	+0.7
3,725,214	-		Rv3339c	0.49	-1.1
3,725,214	-		Rv3339c	0.49	-0.6
3,725,214	-		Rv3339c	0.49	+0.1
3,725,216	-		Rv3339c	0.49	-1.1
3,725,289	-		Rv3339c	0.55	-0.5
3,725,289	-		Rv3339c	0.55	-1.2
3,725,420	+		Rv3339c	0.65	-0.1
3,725,712	-		Rv3339c	0.89	+0.6
3,725,712	-		Rv3339c	0.89	+0.3
3,725,803	+				-2.5
3,725,824	+				-0.1
3,725,865	+				-0.6
3,725,866	-				-1.0
3,725,866	-				+0.1
3,725,885	+				-1.5
3,725,944	+				+0.7
3,725,945	-				+0.1
3,725,945	-				+0.1
3,726,058	+				+0.4
3,726,502	+		Rv3340	0.28	-0.7
3,727,111	+		Rv3340	0.73	-1.1
3,727,111	+		Rv3340	0.73	-0.5
3,727,111	+		Rv3340	0.73	-0.1
3,727,389	+				-2.1
3,727,504	+				-0.5
3,727,504	+				-0.5