Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3318

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
3,704,013	+				-0.7
3,704,084	+				+1.5
3,704,101	+				+0.4
3,704,102	-				-1.1
3,704,116	-				+1.4
3,704,205	-		Rv3316	0.30	+1.5
3,704,263	-		Rv3316	0.47	+0.7
3,704,339	+		Rv3316	0.70	+1.2
3,704,755	+		Rv3317	0.73	+0.5
3,704,836	+				-1.4
3,704,836	+				-0.7
3,704,836	+				+1.0
3,704,844	-				-1.0
3,705,019	-				+1.2
3,705,089	+				+3.3
3,705,112	-				+2.3
3,705,400	-		Rv3318	0.23	-0.2
3,705,627	+		Rv3318	0.35	+1.3
3,705,629	+		Rv3318	0.35	-0.1
3,705,757	+		Rv3318	0.43	+1.3
3,705,927	+		Rv3318	0.52	-0.9
3,705,928	-		Rv3318	0.52	+1.8
3,705,928	-		Rv3318	0.52	+0.4
3,705,934	-		Rv3318	0.53	+1.7
3,706,062	+		Rv3318	0.60	+0.6
3,706,208	+		Rv3318	0.68	+1.7
3,706,252	-		Rv3318	0.71	-0.4
3,706,618	-				+0.5
3,706,767	+				-2.3
3,706,770	+				-0.7
3,706,771	-				+1.4
3,706,961	+		Rv3319	0.24	+0.9
3,706,962	-		Rv3319	0.24	-1.3
3,706,962	-		Rv3319	0.24	-0.1
3,706,974	-		Rv3319	0.26	-0.5
3,706,974	-		Rv3319	0.26	+1.2
3,707,195	+		Rv3319	0.53	-0.8
3,707,213	+		Rv3319	0.56	-0.1
3,707,280	-		Rv3319	0.64	-0.3
3,707,354	+		Rv3319	0.73	-0.1
3,707,751	+		Rv3320c	0.25	-1.2