Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3294c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
3,674,694	+		Rv3293	0.74	+2.7
3,674,697	+		Rv3293	0.74	-0.9
3,674,697	+		Rv3293	0.74	-0.8
3,674,698	-		Rv3293	0.74	-0.4
3,674,698	-		Rv3293	0.74	-2.9
3,674,698	-		Rv3293	0.74	+0.4
3,674,772	+		Rv3293	0.79	+0.8
3,674,784	+		Rv3293	0.80	-0.2
3,674,784	+		Rv3293	0.80	-0.4
3,675,043	-				-0.6
3,675,187	+				-0.6
3,675,187	+				-0.2
3,675,336	-		Rv3294c	0.19	+0.4
3,675,408	+		Rv3294c	0.27	-0.7
3,675,408	+		Rv3294c	0.27	-0.6
3,675,408	+		Rv3294c	0.27	+0.8
3,675,408	+		Rv3294c	0.27	-2.9
3,675,652	-		Rv3294c	0.58	+0.0
3,675,667	+		Rv3294c	0.59	-0.3
3,675,704	+		Rv3294c	0.64	+0.6
3,675,705	-		Rv3294c	0.64	+0.1
3,675,709	-		Rv3294c	0.65	-0.1
3,675,709	-		Rv3294c	0.65	+0.9
3,675,709	-		Rv3294c	0.65	+0.1
3,675,728	+		Rv3294c	0.67	+0.8
3,675,729	-		Rv3294c	0.67	+0.4
3,675,732	+		Rv3294c	0.67	+2.3
3,675,746	+		Rv3294c	0.69	-0.2
3,675,771	+		Rv3294c	0.72	+0.5
3,675,771	+		Rv3294c	0.72	-1.2
3,675,772	-		Rv3294c	0.72	-2.5
3,675,772	-		Rv3294c	0.72	-0.8
3,675,860	+		Rv3294c	0.83	-0.6
3,675,905	+		Rv3294c	0.89	-0.7
3,675,905	+		Rv3294c	0.89	+0.6
3,675,906	-		Rv3294c	0.89	-1.3
3,675,926	-				+0.3
3,675,947	-				+0.2
3,676,046	-				-1.4
3,676,053	+				-2.2
3,676,053	+				-0.8
3,676,054	-				-0.9
3,676,054	-				-0.4
3,676,056	+				+1.7
3,676,057	-				-0.1
3,676,153	+		Rv3295	0.13	+0.3
3,676,153	+		Rv3295	0.13	+1.7
3,676,213	+		Rv3295	0.22	-0.8
3,676,213	+		Rv3295	0.22	+0.7
3,676,214	-		Rv3295	0.22	-0.4
3,676,214	-		Rv3295	0.22	+1.3
3,676,214	-		Rv3295	0.22	+0.9
3,676,214	-		Rv3295	0.22	-0.5
3,676,214	-		Rv3295	0.22	+0.2
3,676,214	-		Rv3295	0.22	+1.0
3,676,214	-		Rv3295	0.22	+0.2
3,676,219	+		Rv3295	0.23	-0.2
3,676,279	+		Rv3295	0.32	-0.3
3,676,280	-		Rv3295	0.32	-0.2
3,676,331	+		Rv3295	0.40	-0.1
3,676,331	+		Rv3295	0.40	+0.0
3,676,332	-		Rv3295	0.40	+0.7
3,676,332	-		Rv3295	0.40	-0.1
3,676,332	-		Rv3295	0.40	+0.3
3,676,351	+		Rv3295	0.43	-1.7
3,676,351	+		Rv3295	0.43	+0.3
3,676,351	+		Rv3295	0.43	-0.5
3,676,351	+		Rv3295	0.43	-0.8
3,676,351	+		Rv3295	0.43	+0.1
3,676,351	+		Rv3295	0.43	+0.9
3,676,351	+		Rv3295	0.43	-0.8
3,676,351	+		Rv3295	0.43	+0.1
3,676,351	+		Rv3295	0.43	-0.3
3,676,351	+		Rv3295	0.43	+0.2
3,676,352	-		Rv3295	0.43	+0.7
3,676,352	-		Rv3295	0.43	+0.2
3,676,353	+		Rv3295	0.43	+1.2
3,676,354	-		Rv3295	0.43	-1.2
3,676,360	+		Rv3295	0.44	-0.5
3,676,361	-		Rv3295	0.44	+0.6
3,676,361	-		Rv3295	0.44	-0.1
3,676,772	+				+0.1
3,676,966	+				-0.2
3,676,966	+				-0.8
3,676,987	+				-0.6
3,676,987	+				-1.8
3,676,988	-				+0.2