Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3141

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
3,507,357	-		Rv3140	0.47	-0.6
3,507,357	-		Rv3140	0.47	-1.9
3,507,612	-		Rv3140	0.68	-0.7
3,507,646	-		Rv3140	0.71	-1.5
3,508,225	+		Rv3141	0.13	-0.8
3,508,246	-		Rv3141	0.16	-1.7
3,508,470	+		Rv3141	0.39	+1.3
3,508,471	-		Rv3141	0.39	-0.7
3,508,723	+		Rv3141	0.65	+2.9
3,508,871	-		Rv3141	0.80	-0.5
3,508,943	-		Rv3141	0.87	+0.6
3,508,943	-		Rv3141	0.87	-0.7
3,508,980	+				-0.1
3,509,047	+				+0.3
3,509,047	+				-0.7
3,509,050	+				+0.3
3,509,051	-				-0.2
3,509,143	-				-0.7
3,509,210	-		Rv3142c	0.21	-0.8
3,509,210	-		Rv3142c	0.21	+3.3
3,509,296	+		Rv3142c	0.41	+2.5
3,509,296	+		Rv3142c	0.41	-0.0
3,509,425	-		Rv3142c	0.72	+4.9
3,509,430	+		Rv3142c	0.73	-0.6
3,509,452	+		Rv3142c	0.78	-0.0
3,509,453	-		Rv3142c	0.78	-1.1
3,509,453	-		Rv3142c	0.78	-0.1
3,509,489	+		Rv3142c	0.86	-1.0
3,509,489	+		Rv3142c	0.86	-1.7
3,509,546	+				+1.3
3,509,546	+				-0.7
3,509,546	+				-0.2
3,509,547	-				-1.4
3,509,547	-				+0.5
3,509,548	+				+0.7
3,509,548	+				-0.7
3,509,549	-				+2.3
3,509,549	-				-0.1
3,509,574	+				+0.3
3,509,575	-				-0.0
3,509,575	-				+1.0
3,509,583	+				-0.0
3,509,583	+				+1.3
3,509,584	-				+1.9
3,509,641	-				+1.1
3,509,691	-				+0.9
3,509,771	+		Rv3143	0.29	-0.5
3,509,803	-		Rv3143	0.37	+1.9